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In Vitro High-Throughput RNAi Screening to Accelerate the Process of Target Identification and Drug Development

Methods in Molecular Biology

Sep 2, 2016

Hongwei Yin, Michelle Kassner

Abstract

High-throughput RNA interference (HT-RNAi) is a powerful tool that can be used to knock down gene expression in order to identify novel genes and pathways involved in many cellular processes. It is a systematic, yet unbiased, approach to identify essential or synthetic lethal genes that...read more

Mentioned in this Paper

Drug Development
Biochemical Pathway
Cellular Process
Gene Knockdown Techniques
Genes
RNA, Small Interfering
Cosuppression
High Throughput Screening
Gene Expression
Clinician
1
3
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In Vitro High-Throughput RNAi Screening to Accelerate the Process of Target Identification and Drug Development

Methods in Molecular Biology

Sep 2, 2016

Hongwei Yin, Michelle Kassner

PMID: 27581290

DOI: 10.1007/978-1-4939-6337-9_11

Abstract

High-throughput RNA interference (HT-RNAi) is a powerful tool that can be used to knock down gene expression in order to identify novel genes and pathways involved in many cellular processes. It is a systematic, yet unbiased, approach to identify essential or synthetic lethal genes that...read more

Mentioned in this Paper

Drug Development
Biochemical Pathway
Cellular Process
Gene Knockdown Techniques
Genes
RNA, Small Interfering
Cosuppression
High Throughput Screening
Gene Expression
Clinician
1
3

Similar Papers Found In These Feeds

Drug & Digital Interventions

This feed describes how digital interventions, which are digital and mobile technologies used to support health system needs, can complement and improve pharmacotherapy in disease management. Discover the latest research on drug and digtial intervention here,

RNAi & Gene Silencing

RNA Interference (RNAi) pathway is involved in post-transcriptional gene silencing, transcriptional silencing and epigenetic silencing as well as its use as a tool for forward genetics and therapeutics. Discover the latest research here.

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High-Throughput Screening of Tyrosine Kinase Inhibitor Resistant Genes in CML

Methods in Molecular BiologySeptember 2, 2016
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Establishing an Infrastructure for High-Throughput Short-Interfering RNA Screening

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Paper Details
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  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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