In vitro influence of theophylline on anti-IgE-induced release from leucocytes and whole blood in asthmatic children

Agents and Actions
P ScheinmannJ Fermanian

Abstract

Two groups of asthmatic children were found with regard to the influence of theophylline on the anti-IgE-induced histamine release from whole blood. In th first group (21 children), histamine release was obtained both from whole blood and washed leucocytes and was inhibited by 10(-4) M theophylline. In the second group (5 children), histamine release required the presence of plasma and was not inhibited by 10(-4) M theophylline. Theophylline treatment was efficacious only in children of the first group.

References

Jan 1, 1975·International Archives of Allergy and Applied Immunology·R P Siraganian, B B Levine
Aug 30, 1968·Science·L M Lichtenstein, S Margolis

❮ Previous
Next ❯

Related Concepts

Related Feeds

Asthma

This feed focuses in Asthma in which your airways narrow and swell. This can make breathing difficult and trigger coughing, wheezing and shortness of breath.

Allergy and Asthma

Allergy and asthma are inflammatory disorders that are triggered by the activation of an allergen-specific regulatory t cell. These t cells become activated when allergens are recognized by allergen-presenting cells. Here is the latest research on allergy and asthma.