In vitro investigation of antimicrobial activities of ethnomedicinal plants against dental caries pathogens

3 Biotech
Mamta Besra, Vipin Kumar

Abstract

The study aimed to evaluate the antimicrobial activity of medicinal plant extracts against the bacterial pathogens prominent in dental caries. A total of 20 plant species (herbs, shrubs and trees) belonging to 18 genera and 15 families were documented for dental caries. Antimicrobial activity of solvent extracts and essential oil from plants were determined by zone of inhibition on the growth of Streptococcus mutans (MTCC 497) and Lactobacillus acidophilus (MTCC 10307) using the agar well diffusion method. The results of in vitro antimicrobial assay prove that methanol is more successful in the extraction of phytochemicals from plant samples than aqueous solvent, as methanol extracts show higher antimicrobial activity than aqueous extracts against both the test pathogens. Methanol extracts of Nigella sativa, Psidium guajava and Syzygium aromaticum were the most effective among all 20 plant samples and have potent inhibitory activity against both dental caries pathogens with minimum inhibitory concentration of 0.2 mg mL- 1. N. sativa seed methanol extract was more effective with 22.3 mm zone of inhibition at 0.2 mg mL- 1 against S. mutans (MTCC 497), while L. acidophilus (MTCC 10307) was more sensitive to S. aromaticum bud metha...Continue Reading

References

Jun 1, 1975·Infection and Immunity·W J LoescheP J Loos
May 13, 2004·Journal of Ethnopharmacology·Jittra LimsongJintakorn Kuvatanasuchati
Oct 17, 2007·Annual Review of Medicine·A Simon Lynch, Gregory T Robertson
Oct 2, 2008·Journal of Ethnobiology and Ethnomedicine·Bharat K Pradhan, Hemant K Badola
Apr 29, 2009·Journal of Ethnopharmacology·Fábio C SampaioMarília A R Buzalaf
Apr 29, 2015·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Irlan Almeida FreiresPedro Luiz Rosalen
May 27, 2015·Pharmacognosy Reviews·T LakshmiN Madhusudhanan

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Citations

Apr 26, 2021·Archives of Oral Biology·Manali Deb BarmaBennett T Amaechi

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