In vitro lymphocyte reactivity to rubella antigen following vaccination

Scandinavian Journal of Infectious Diseases
Z HeiglM Forsgren

Abstract

In vitro lymphocyte stimulation and several serological tests were used to study the development of immunity after subcutaneous immunization with attenuated rubella virus. Maximal lymphocyte reactivity was obtained 3--4 months after vaccination and a decline after 1.5--2.5 years. Lymphocyte reactivity following natural immunity was of a higher magnitude. No correlation between the degree of lymphocyte stimulation and titers of neutralizing, hemagglutination inhibiting and hemolysis-in-gel antibodies was observed. The influence on the results of some methodological factors and different rubella antigens is discussed.

References

Jan 1, 1975·Archives of Virology·R Cappel
Nov 2, 1968·Lancet·M J Simons, M G Fitzgerald
May 1, 1971·American Journal of Epidemiology·A FogelC B Gerichter
Oct 23, 1965·Nature·G J Johnson, P S Russell
May 1, 1967·Proceedings of the Society for Experimental Biology and Medicine·P D HalonenA D Hall
Feb 1, 1952·Proceedings of the Society for Experimental Biology and Medicine·A SVEDMYRA HOLLOWAY

Citations

May 1, 1983·Archives of Disease in Childhood·C S HoskingB Wilkins

Related Concepts

Teens
Antibodies, Viral
Antigens, Viral
Cell Separation
Antibody Dissociation
Differential White Blood Cell Count Procedure
Lymphocyte Activation
Lymphoid Cells
Rubella virus vaccine
Rubella virus

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