In vitro performance testing of a pediatric oxygenator with an integrated pulsatile pump

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
Ralf BorchardtUlrich Steinseifer

Abstract

For different lung and heart diseases (e.g., acute respiratory distress syndrome, congenital heart failure, and cardiomyopathy) extracorporeal membrane oxygenation is a well-established therapy, particularly in the field of neonatal and pediatric medicine. To reduce the priming volume of the extracorporeal circuit, different components can be combined. In this study, an oval-shaped oxygenator (called ExMeTrA) with integrated pulsatile pump was tested in vitro using porcine blood. A feasibility study regarding the performance of collapsing and expanding silicone tubes within an oxygenator fiber bundle as a pulsatile pump was previously completed with successful results. The findings of this study improve upon the previous feasibility results, particularly in terms of gas exchange and filling volume. Five modules were manufactured in sizes of 20 ± 2.2 ml (priming volume) with fiber surface areas of 0.24 ± 0.027 m(2) and an analytically calculated volume pumping capacity of 692 ± 75 ml/min. The modules were made of polymethylpentene fibers with dense outer layer to permit long-term applications. The gas exchange rates at a gas/blood flow ratio of 2:1 were between 64 and 72.7 ml(O)(2)/l(blood) and between 62.5 and 81.5 ml/l(blood),...Continue Reading

References

Sep 1, 1996·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Y OrimeY Sezai
Jan 28, 1998·American Journal of Respiratory and Critical Care Medicine·D Dreyfuss, G Saumon
Nov 30, 2000·Critical Care : the Official Journal of the Critical Care Forum·K Lewandowski
Dec 6, 2003·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Federica BoschettiLyle F Mockros
Dec 12, 2003·The Annals of Thoracic Surgery·William S Haworth
Sep 21, 2004·Perfusion·Giorgio CattaneoHelmut Reul
Mar 5, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Steven A ConradHeidi Dalton
Jun 1, 2005·Seminars in Perinatology·Robert H Bartlett
Oct 20, 2005·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Satoshi Saito, Tomohiro Nishinaka
Dec 3, 2005·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Salvatore AgatiAkif Undar
Mar 25, 2006·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Heide J EashWilliam J Federspiel
Aug 3, 2006·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Bingyang Ji, Akif Undar
Mar 24, 2007·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Eisuke Tatsumi
Sep 25, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Jutta ArensUlrich Steinseifer
Dec 19, 2008·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Nikkole M HainesAkif Undar
Mar 19, 2009·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·George M PantalosMark Gartner
Nov 26, 2010·Artificial Organs·David PalanzoAkif Undar
Nov 26, 2010·Artificial Organs·Ralf BorchardtUlrich Steinseifer
Nov 26, 2010·Artificial Organs·Heike SchnoeringJaime F Vazquez-Jimenez
Apr 5, 2011·The International Journal of Artificial Organs·Marcus HormesUlrich Steinseifer
Oct 7, 2011·Artificial Organs·Sonya S BhavsarUlrich Steinseifer

❮ Previous
Next ❯

Citations

Jun 23, 2015·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Katharina StangHans-Peter Wendel
Mar 7, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Jutta ArensRolf Rossaint
Jan 16, 2015·The International Journal of Artificial Organs·R Garrett JeffriesPeter D Wearden
Mar 25, 2014·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Venkat ShankarramanChristian A Bermudez
Sep 8, 2017·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Erin SchumerBettina Wiegmann
Jul 17, 2018·Interactive Cardiovascular and Thoracic Surgery·Christian BleilevensAndreas Goetzenich
Aug 3, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Jutta ArensRolf Rossaint
May 21, 2020·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Christian KaragiannidisDaniel Brodie

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.

Related Papers

ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
A J MakarewiczC Mavroudis
ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs
A FunakuboY Nosé
© 2021 Meta ULC. All rights reserved