PMID: 7026459Sep 15, 1980Paper

In vitro reaction of cancer patients and others to Bacillus Calmette-Gueérin

International Journal of Cancer. Journal International Du Cancer
G ToddL J Morrison

Abstract

We examined the in vitro reaction of leukocytes from 71 cancer patients and 121 control donors (disease-free individuals or patients with non-malignant non-debilitating conditions) against Bacillus Calmette-Guérin using a one-stage capillary leukocyte migration assay. The proportion of reactive cancer patients and control donors increased with increasing BCG concentration, but the proportion of patients who reacted was less than that of control donors at all concentrations of BCG. As cancer stage advanced and the volume of clinically detectable tumor increased, the proportion of reactive patients decreased. There was a small age-related decline in reactivity in the control population. The results of simultaneous in vitro tests and Mantoux reactions were concurrent in a majority of normal individuals so tested.

References

Jan 1, 1979·Journal of Surgical Oncology·G V AranhaT B Grage
Sep 15, 1976·International Journal of Cancer. Journal International Du Cancer·A J CochranA M Jackson
Jan 1, 1973·International Archives of Allergy and Applied Immunology·R H WeisbartL S Goldberg
Sep 1, 1973·Journal of Clinical Pathology·A M Jokipii, L Jokipii
May 1, 1968·The Journal of Pediatrics·N MatsaniotisC Metaxotou-Stavridaki
Dec 1, 1969·Proceedings of the Society for Experimental Biology and Medicine·M D Lockshin
Feb 1, 1967·Acta Medica Scandinavica·M Soborg, G Bendixen

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.