Jan 1, 1979

In vitro release of eosinophil chemotactic factor of anaphylaxis (ECF-A) from guinea pig skin

International Archives of Allergy and Applied Immunology
I KimuraT Yamura

Abstract

An in vitro release of the eosinophil chemotactic factor of anaphylaxis (ECF-A) in anaphylactic reactions was studied using skin slices from actively sensitized guinea pigs. ECF-A and histamine were released in vitro from actively sensitized guinea pig skin by antigen challenge. The magnitude of ECF-A release did not always parallel that of anaphylactic histamine release in guinea pig skin, suggesting that there may be no correlation between the amount of ECF-A and that of histamine released from the skin in anaphylactic reactions in guinea pigs.

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Mentioned in this Paper

Histamine Measurement
Eosinophil
Anaphylaxis (Non Medication)
Mast Cell
Cavia
Hemolytic Complement
Antigens
Macrophage Chemotactic Factors
Anaphylaxis
Skin

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Anaphylaxis

Anaphylaxis is a serious allergic reaction that is rapid in onset and may cause death.

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