PMID: 13695749Jul 1, 1961Paper

In vitro studies of the gain and exchange of calcium in frog skeletal muscle

The Journal of General Physiology


(1) The Ca(++), Na(+), and K(+) contents of frog sartorius muscles were found analytically after exposure to various media including some containing labeled Ca(++). (2) During storage in media with 100 to 120 mM Na(+) and 1 mM Ca(++) both Na(+) and Ca(++) are gained while K(+) is lost; there is a high correlation between Na(+) and Ca(++) gains. (3) When Ca(++) gain occurs from a solution containing labeled Ca(++) there is also some exchange of the original Ca(++) with the labeled Ca(++). The amount exchanged is considerably less (e.g. 50 per cent) than the total amount of labeled Ca(++) taken up by the tissue. (4) When the external Na(+) concentration is reduced to 30 mM the amount of labeled Ca(++) taken up is increased. Part of the increase is attributable to a greater net gain and part to a greater degree of exchange. (5) It is pointed out that muscles which have been loaded in vitro with labeled Ca(++) will not provide a valid measure of the exchangeability of the normal Ca(++) content present at the time of dissection. (6) Comparison is made between results obtained using Sr(89) and Ca(45) as labels for the Ca(++). Little, if any, difference is perceptible.


Nov 20, 1956·The Journal of General Physiology·M E HOLMANS E SIMON
Jan 20, 1957·The Journal of General Physiology·W O Fenn, D L GILBERT
Mar 20, 1959·The Journal of General Physiology·C P BIANCHI, A M SHANES


Dec 1, 1964·Journal of Cellular Physiology·J D JUDAH, K AHMED
Dec 1, 1964·Journal of Cellular Physiology·J D JUDAH, D A WILLOUGHBY
Jan 1, 1982·The Journal of Membrane Biology·J R Gilbert, G Meissner
Jan 1, 1982·The Journal of Membrane Biology·R A Sjodin
Jun 22, 1978·The Journal of Membrane Biology·C Caputo, P Bolaños
Jun 18, 1962·Biochimica Et Biophysica Acta·S E SIMOND G SATCHELL
Jan 1, 1972·Progress in Biophysics and Molecular Biology·P F Baker
Jan 1, 1980·Progress in Biophysics and Molecular Biology·P V Sulakhe, P J St Louis
Apr 28, 1962·Nature·J D JUDAH, K AHMED
Sep 1, 1968·The Journal of General Physiology·L A Beauge, R A Sjodin
Nov 1, 1969·The Journal of General Physiology·R A Sjodin, L A Beauge
Oct 1, 1974·The Journal of General Physiology·R Dipolo
May 1, 1964·Biological Reviews of the Cambridge Philosophical Society·J D JUDAH, K AHMED
Apr 1, 1993·Acta Physiologica Scandinavica·M E EvertsT Clausen
Jan 1, 1991·Annals of the New York Academy of Sciences·E CastilloM Rozycka
Feb 1, 1972·CRC Critical Reviews in Biochemistry·H RasmussenA Tenenhouse
Dec 1, 1971·Journal of Cellular Physiology·H K Borys, R Karler
Apr 15, 1996·Annals of the New York Academy of Sciences·H Gonzalez-SerratosH Rasgado-Flores
May 2, 2003·The Journal of Comparative Neurology·Michele PapaLucio Annunziato
Aug 20, 1981·Biochimica Et Biophysica Acta·S Yamamoto, K Greeff
Jan 1, 1962·Analytical Biochemistry·E COSMOS
Mar 16, 1973·Biochimica Et Biophysica Acta·R Dipolo
May 7, 1982·Biochimica Et Biophysica Acta·C Deutsch, M A Price
Nov 3, 1962·Nature·J D JUDAHA E MCLEAN
Oct 1, 1991·Journal of Muscle Research and Cell Motility·M C GarciaM Rozycka
Aug 27, 1964·Annals of the New York Academy of Sciences·A E MCLEANJ D JUDAH
Oct 1, 1988·Journal of Muscle Research and Cell Motility·B A Curtis
Jul 3, 1999·Physiological Reviews·M P Blaustein, W J Lederer
Feb 15, 1964·Klinische Wochenschrift·K REPKE
Jun 1, 1992·Journal of Muscle Research and Cell Motility·M C GarciaJ A Sanchez

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