Abstract
Bidens pilosa is an annual plant from tropical America with anti-inflammatory properties in hepatitis, laryngitis, headache and digestive disorders, among others. Its wide pharmacological applications can be attributed to its chemical composition, with inhibitory effects on pathogenic microorganisms and flavonoids, which show strong antioxidant capacities. We investigated the antioxidant activity of an aqueous infusion of Bidens pilosa by studying its protective effect on the hemolysis induced by an initiator of radicals such as 2,2'-azobis(2-amidinopropane) dihydrochloride (AAPH). The immunomodulatory activity of the infusion was tested using whole blood cells. Cytokine production increased in whole blood stimulated or not by lipopolysaccharides (LPSs). The infusion is also characterized by its capacity to protect erythrocytes from the phototoxic effect of chlorpromazine, which allows its use as a potential photoprotector. Finally, it did not show ocular irritation, as demonstrated by the effect on hemoglobin denaturation. This study supports the health benefits of the ingestion of the infusion.
References
Jan 1, 1987·Free Radical Research Communications·M R ClemensH D Waller
Nov 1, 1987·Archives of Biochemistry and Biophysics·M MikiE Niki
Jul 1, 1986·The Biochemical Journal·C Rice-EvansE Baysal
Jul 18, 1995·Biochemistry·Y SatoY Suzuki
Apr 1, 1995·Biological & Pharmaceutical Bulletin·T HayashiY Suzuki
Jan 1, 1994·Life Sciences·Y WangR R Watson
Sep 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·B N AmesT M Hagen
Jan 1, 1996·Free Radical Biology & Medicine·C A Rice-EvansG Paganga
Jan 1, 1997·Free Radical Biology & Medicine·F N KoY H Kuo
Jan 1, 1997·Dermatology : International Journal for Clinical and Investigative Dermatology·B Eberlein-KönigB Przybilla
Mar 1, 1997·Journal of Ethnopharmacology·T Rabe, J van Staden
Jul 1, 1997·Journal of Ethnopharmacology·M G BrandãoH C Marinuzzi
Aug 7, 1999·Immunopharmacology·R L PereiraV L Gonçalves de Moraes
Jun 24, 2000·Transfusion·K MascottiS R Burger
Dec 13, 2000·Phytotherapy Research : PTR·R Gomez-FloresR J Weber
Mar 28, 2003·Life Sciences·G RimbachL Packer
Apr 2, 2003·Journal of Immunological Methods·Corinna HermannThomas Hartung
Feb 1, 1988·Planta medica·B Hoffmann, J Hölzl
Citations
Jul 4, 2013·Journal of Dermatological Science·Futoshi KohdaMasutaka Furue
Jul 29, 2010·Journal of Ethnobiology and Ethnomedicine·Mainen J MoshiAnke Weisheit
Jan 17, 2012·Journal of Clinical Biochemistry and Nutrition·Jin-Sang KilHyun-Ock Pae
Oct 23, 2013·African Journal of Traditional, Complementary, and Alternative Medicines : AJTCAM·Li-Hong ZhuYing Pan
Mar 18, 2008·Journal of Ethnopharmacology·Maicon Roberto KviecinskiRozangela Curi Pedrosa
May 20, 2008·Journal of Ethnopharmacology·Ronaldo de Jesus CostaBerenice Quinzani Jordão
Mar 4, 2008·Journal of Ethnopharmacology·Li-Ping YuanLi-Juan Xia
Nov 15, 2006·Journal of Ethnopharmacology·Yi-Ming ChiangLie-Fen Shyur
Oct 17, 2012·Journal of Ethnopharmacology·Sebua SemenyaAlfred Maroyi
Feb 27, 2017·Journal of Inorganic Biochemistry·Lucas B BolzonMarilda D Assis
Nov 6, 2018·Drug and Chemical Toxicology·Cristiane Martinez Ruiz PegoraroMarcos Alberto Zocoler
Apr 18, 2008·The Journal of Pharmacy and Pharmacology·Agnieszka MaruszewskaJolanta Tarasiuk
Apr 17, 2015·Journal of Leukocyte Biology·Wen-Chi WeiNing-Sun Yang
Oct 7, 2019·Journal of Insect Science·Julián Hernández-CruzCarlos A Granados-Echegoyen
Oct 4, 2014·International Journal of Immunopathology and Pharmacology·M AkramA Naveed
Jan 1, 2016·Journal of Pharmaceutical Investigation·Tran Dang Xuan, Tran Dang Khanh
Dec 10, 2019·Journal of Ethnopharmacology·S van Vuuren, L Frank
Aug 27, 2021·Journal of Ethnopharmacology·L J McGawJ Van Staden