In vitro study of the aortic interleaflet triangle reshaping

Journal of Biomechanics
R VismaraGianfranco B Fiore

Abstract

Aortic interleaflet triangle reshaping (AITR) is a surgical approach to aortic valve incontinence that involves placing three stitches at half of the interleaflet triangles height. In this work, the relationship between the actual stitch height and valve functioning, and the safety margin that the surgeon can rely on in applying the stitches were systematically investigated in vitro. AITR surgery was applied to six swine aortic roots placing the stitches empirically at 50%, 60% and 75% of the triangle heights. Then the actual stitch heights were measured and the hydrodynamic performances were evaluated with a pulsatile hydrodynamic mock loop. Actual stitch heights were 45±2%, 61±4% and 79±6%. As compared to untreated conditions, the 50% configuration induced a significant variation in the effective orifice area. With stitches placed at 60%, the mean systolic pressure drop increased significantly with respect to the untreated case, but no significant changes were recorded with respect to the 50% configuration. At 75%, all the hydrodynamic parameters of systolic valve functioning worsened significantly. Summarizing, the AITR technique, when performed in a conservative manner did not induce significant alterations in the hydrodyna...Continue Reading

References

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May 15, 2010·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Riccardo VismaraCarlo Antona
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Citations

Jul 9, 2014·Journal of Biomechanics·Giorgio QuerzoliFrancesca Sorgini
Nov 22, 2014·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Giordano TascaAmando Gamba
May 28, 2016·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Giordano TascaRiccardo Vismara
Jun 22, 2017·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Pallav ShahRiccardo Vismara
May 6, 2017·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Giordano TascaRiccardo Vismara
May 9, 2014·The International Journal of Artificial Organs·Riccardo VismaraCarlo Antona
Nov 25, 2016·Physiological Measurement·Marco PiolaGianfranco Beniamino Fiore
Oct 7, 2017·The International Journal of Artificial Organs·Stefania MarconiFerdinando Auricchio

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