In vitro susceptibility of Mycoplasma hyopneumoniae and Mycoplasma hyorhinis to fifty-one antimicrobial agents.

Antimicrobial Agents and Chemotherapy
P P Williams

Abstract

By a tube dilution assay technique, 51 antimicrobial agents were singly tested against 9 strains of Mycoplasma hyopneumoniae and 1 strain of M. hyorhinis for the purpose of obtaining information useful for selecting an agent for testing in vivo against porcine mycoplasmal pneumonia. Based on determining minimal inhibitory concentrations and chemically grouping the agents into nine classes, all M. hyopneumoniae strains were found resistant to penicillins and peptides and susceptible to sulfonamides and tetracyclines, and, in other classes, were either susceptible or resistant depending on the particular agent being tested. Strains were susceptible to the same 33 of the 51 agents. Minimal inhibitory concentrations ranged from 0.06 to 9.20 mug/ml. M. hyorhinis was susceptible to 19 of the 33 agents that M. hyopneumoniae was susceptible to. Minimal inhibitory concentrations ranged from 0.03 to 8.10 mug/ml. All strains of M. hyopneumoniae differed from M. hyorhinis in that they were susceptible to cephaloglycin and nitrofurazone.

Citations

Dec 1, 1978·Journal of Helminthology·L S Blair, W C Campbell
Feb 1, 1991·Antimicrobial Agents and Chemotherapy·E A Ter LaakJ H Verheijden
Oct 25, 2016·Veterinary Microbiology·Beth S CookAndrew N Rycroft
Jun 20, 2020·The Veterinary Journal·Dominiek MaesAnne V Gautier-Bouchardon
Apr 1, 1996·Antimicrobial Agents and Chemotherapy·H KobayashiK Yamamoto

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