In Vitro Validation of the Lesion Size Index to Predict Lesion Width and Depth After Irrigated Radiofrequency Ablation in a Porcine Model

JACC. Clinical Electrophysiology
Vittorio CalzolariZoran Olivari

Abstract

In an in vitro model, the authors tested the hypotheses that: 1) lesion dimensions correlate with lesion size index (LSI); and 2) LSI could predict lesion dimensions better than power, contact force (CF), and force-time integral (FTI). When performing radiofrequency (RF) catheter ablation for cardiac arrhythmias, reliable predictors of lesion quality are lacking. The LSI is a multiparametric index incorporating time, power, CF, and impedance recorded during ablation. RF lesions were created on porcine myocardial slabs by using an open-tip irrigated catheter capable of real-time monitoring of catheter-tissue CF. Initially, 3 power settings of 20, 25, and 30 W were used with a fixed CF of 10 g. A fixed power of 20 W was then set with a CF of 20 and 30 g, thereby yielding a total of 5 ablation groups. In each group, LSI values of 5, 6, 7, and 8 were targeted. Sixty RF lesions were created by using 20 ablation protocols (3 lesions for each protocol). Lesion width and depth were not correlated with power or CF, but the results significantly correlated with FTI (p < 0.01) and LSI (p < 0.0001). Four steam pops occurred with power set at 30 W; no pops were noted with 20 or 25 W even when high LSI values were targeted. In this in vitro ...Continue Reading

References

Apr 8, 1999·Pacing and Clinical Electrophysiology : PACE·S S ChughD L Packer
Nov 15, 2006·Pacing and Clinical Electrophysiology : PACE·Fred H M Wittkampf, Hiroshi Nakagawa
May 1, 2015·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Sven KnechtMichael Kühne
Jun 5, 2015·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Josef KautznerKarl-Heinz Kuck

❮ Previous
Next ❯

Citations

Dec 13, 2019·Journal of Cardiovascular Electrophysiology·Maria TerricabrasAtul Verma
Nov 13, 2019·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Sergio Castrejón-CastrejónJosé Luis Merino
Jun 13, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Marc Kottmaier
Aug 7, 2020·Journal of Cardiovascular Electrophysiology·Felix BourierPierre Jais
Aug 19, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Dong Geum ShinHong Euy Lim
Aug 31, 2020·Europace : European Pacing, Arrhythmias, and Cardiac Electrophysiology : Journal of the Working Groups on Cardiac Pacing, Arrhythmias, and Cardiac Cellular Electrophysiology of the European Society of Cardiology·Adam IoannouRui Providencia
Sep 11, 2018·Circulation Journal : Official Journal of the Japanese Circulation Society·Paula MünklerRoland Richard Tilz
Sep 1, 2018·Journal of Cardiovascular Electrophysiology·Felix BourierPierre Jais
Oct 26, 2018·Journal of Cardiovascular Electrophysiology·Parin J Patel, Benzy J Padanilam
Dec 6, 2018·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Antonio Dello RussoClaudio Tondo
Mar 19, 2019·Circulation. Arrhythmia and Electrophysiology·José Manuel Alfonso-AlmazánDavid Filgueiras-Rama
Sep 4, 2018·Journal of Cardiovascular Electrophysiology·Naomi KanamoriMasayuki Takamura
Jul 10, 2020·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Robbert RamakCarlo de Asmundis
Feb 25, 2020·Pacing and Clinical Electrophysiology : PACE·Abdul S ParwaniLeif-Hendrik Boldt
Apr 15, 2018·Circulation. Arrhythmia and Electrophysiology·John WhitakerMark D O'Neill
Sep 9, 2020·Circulation. Arrhythmia and Electrophysiology·Milena LeoTimothy R Betts
Feb 2, 2021·Korean Circulation Journal·Dong Geum Shin, Hong Euy Lim
Mar 6, 2021·Journal of Arrhythmia·Riccardo ProiettiTarvinder Dhanjal
Jun 23, 2021·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Masateru TakigawaTetsuo Sasano
Aug 29, 2021·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Josip KatićZrinka Jurišić
Oct 13, 2021·Scientific Reports·Soo Young ParkChristine Hendon
Jan 9, 2022·Journal of Interventional Cardiac Electrophysiology : an International Journal of Arrhythmias and Pacing·Cristina Lozano GraneroJavier Moreno

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.

Atrial Fibrillation

Atrial fibrillation is a common arrhythmia that is associated with substantial morbidity and mortality, particularly due to stroke and thromboembolism. Here is the latest research.

© 2022 Meta ULC. All rights reserved