In vivo activity of amoxicillin and ampicillin against gram-positive bacteria: results of prophylactic studies

The Journal of Infectious Diseases
E GrunbergW DeLorenzo

Abstract

In prophylactic treatment of intraperitoneal infections with Streptococcus pneumoniae (types 1 and 2) and Streptococcus pyogenes in mice, amoxicillin had a definite advantage over ampicillin in terms of protective effect. When the infecting agent was given to mice so as to produce an infection in the brain or lung (for example, S. pneumoniae given intracranially or intranasally), amoxicillin was also more effective prophylactically than ampicillin.

Citations

Sep 1, 2015·PLoS Computational Biology·Chengsheng ZhuYana Bromberg
Mar 1, 1987·The Journal of International Medical Research·A FasslG Nahler

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