In vivo anthelmintic activity of Phytolacca icosandra against Haemonchus contortus in goats

Veterinary Parasitology
M M Hernández-VillegasM Cáceres-Farfan

Abstract

The in vivo anthelmintic (AH) activity of the ethanolic extract from leaves of Phytolacca icosandra was evaluated in goats artificially infected with Haemonchus contortus. Parasite naïve goats were artificially infected with 3000 H. contortus infective larvae per animal. Once the infection was patent (day 28 post-infection) all the animals were sampled to determine the faecal egg counts (FEC) for five consecutive days. Two groups of animals were formed balanced for their FEC and body-weight (BW) (n=6/group): the non-treated control group and the treated group in which goats were individually administered with the ethanolic extract of P. icosandra. The extract was administered orally using gelatin capsules (250 mg/kg BW) which were dosed on two consecutive days using a pill-dispenser. Faecal samples were collected from each animal from the day of dosage (Day 0) on a daily basis to determine the number of eggs per gram of feces (EPG) for 15 days post-treatment (PT). The FEC of the two groups were compared using the repeated measures analyses of variance using the log transformed data Ln (FEC+1). The presence of saponins, coumarins, flavonoids, steroids and terpenoids were detected by standard methodologies in the extract. The P. ...Continue Reading

References

Feb 1, 1997·International Journal for Parasitology·D R Hennessy
Dec 29, 2000·Phytochemistry·V TreyvaudK Hostettmann
Dec 21, 2002·The British Journal of Nutrition·George FrancisKlaus Becker
Sep 15, 2004·Trends in Parasitology·Ray M Kaplan
Dec 14, 2004·Phytochemistry·Michael SchwarzHeidrun Anke
Mar 8, 2005·Tropical Animal Health and Production· Hounzangbe-AdoteH Hoste
Jan 13, 2006·Veterinary Parasitology·P J WallerM Törnquist
Jun 6, 2006·Veterinary Parasitology·Frank Jackson, Jim Miller
Jun 24, 2008·Natural Product Research·Xing-Biao WangKe-Qin Zhang
Dec 17, 2008·Veterinary Parasitology·K A TariqA S Shawl
Dec 4, 2009·Applied Microbiology and Biotechnology·Andrew P Desbois, Valerie J Smith
Jan 16, 2010·The Journal of Antibiotics·Sloan AyersSheo B Singh
May 22, 2010·Trends in Parasitology·Hervé HosteIan Beveridge
Jul 8, 2010·Veterinary Parasitology·C Martínez-Ortíz-de-MontellanoJ F J Torres-Acosta
Mar 29, 2011·Veterinary Parasitology·M M Hernández-VillegasM Cáceres-Farfan

❮ Previous
Next ❯

Citations

Jun 21, 2013·Parasitology Research·Mayara de Aquino MesquitaClaudia Maria Leal Bevilaqua
May 6, 2015·Natural Product Research·Elier Galarraga Montes, Juan Manuel Amaro-Luis
Oct 27, 2017·Journal of Helminthology·S S Santa RosaM J M Batatinha
Mar 7, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Beatriz Hernández-Carlos, Marcela Gamboa-Angulo
Jun 7, 2020·Natural Products and Bioprospecting·Elier GalarragaJuan Manuel Amaro-Luis
May 21, 2019·Parasitology·Francianne Oliveira SantosMariana Borges Botura

❮ Previous
Next ❯

Related Concepts

Related Feeds

Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.