In vivo anti-inflammatory activities of Ocimum suave in mice

Journal of Ethnopharmacology
Birhanetensay MasreshaAsfaw Debella

Abstract

Ocimum suave has been used in the Ethiopian traditional medicine to relieve pain, fever, inflammation and other disease conditions. The aim of the present study was to investigate the anti-inflammatory activities of the aqueous and ethanol leaf extracts and some fractions of Ocimum suave in mice. The crude extracts were screened for their anti-inflammatory activities on carrageenan-induced mouse paw edema at three dose levels. The butanol and aqueous fractions of the aqueous extract were also evaluated for their anti-inflammatory activities using carrageenan, histamine and serotonin-induced mouse paw edema at three dose levels. Normal saline and aspirin were employed as negative and positive control groups, respectively. Both ethanol and aqueous extracts significantly decreased carrageenan-induced inflammation at all the three doses used. However, greater paw edema inhibition was observed with the aqueous extract. The two fractions also showed significant reduction of inflammation against inflammatory models in which the aqueous residue exhibited the highest inhibition. From the present findings, it can be concluded that the ethanol and aqueous leaf extracts as well as butanol and aqueous fractions of Ocimum suave have shown an...Continue Reading

References

Jun 18, 2002·Journal of Ethnopharmacology·S SosaAurelia Tubaro
Nov 28, 2002·Pharmacology & Therapeutics·Bent H Havsteen
Nov 5, 2003·Phytotherapy Research : PTR·Eyasu MakonnenFrehiwot Teka
Apr 26, 2005·Journal of Ethnopharmacology·C DelporteO Muñoz
Nov 1, 2005·Yonsei Medical Journal·Joo-Heon Yoon, Seung Joon Baek
Aug 1, 2006·Journal of Ethnopharmacology·Mariamawit YonathanFranz Bucar
Nov 4, 2006·BMC Complementary and Alternative Medicine·M GuptaV Thamil Selvan
Nov 11, 2006·Journal of Ethnopharmacology·Ampai PanthongVichai Reutrakul
Sep 23, 2008·Basic & Clinical Pharmacology & Toxicology·Adeolu A AdedapoAnthony J Afolayan
Apr 21, 2009·Medicinal Research Reviews·Raju Gautam, Sanjay M Jachak
May 1, 2010·Journal of Ethnopharmacology·M William CareyG Krishna Mohan
Jul 27, 2010·Progress in Lipid Research·Melanie J Stables, Derek W Gilroy
Dec 7, 2010·Journal of Ethnopharmacology· Woldesellassie Mequanint Kelbessa Urga
Dec 7, 2010·Biochimie·L KularC Martinerie
Jul 16, 2015·Journal of Experimental Zoology. Part A, Ecological Genetics and Physiology·Hanna Kalamarz-KubiakEwa Kulczykowska

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Citations

Jan 17, 2015·Iranian Red Crescent Medical Journal·Heibatollah SadeghiMostafa Mostafazadeh
Feb 24, 2015·Journal of Inflammation·Petrina KapewangoloDebra Meyer

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