Abstract
The potential of multislice CT (MSCT) to predict coronary spasm has not been elucidated. The aim of this study was to investigate whether the morphological features observed on MSCT at the site of ergonovine-induced epicardial spasm could be used as diagnostic criteria for coronary spasm. A total of 296 plaques in 199 patients with clinically suspected coronary spastic angina without coronary stenosis (<75%) who underwent invasive angiography with intravenous ergonovine provocative testing were analyzed by MSCT. Calcification, CT attenuation, and patterns of vascular remodeling were evaluated in each plaque by MSCT. Plaques were divided into spasm group or nonspasm group based on the results of the ergonovine provocative test. On a per-plaque basis, noncalcified plaques were more frequently observed in the spasm group (96% versus 20%, P<0.01). Intermediate attenuation plaques (CT density ≥53.8 Hounsfield units identified by receiver operating characteristic analysis) were more common in the spasm group (93% versus 28%, P<0.01), as was negative remodeling (67% versus 11%, P<0.01). Multivariable analysis revealed noncalcified (odds ratio [OR], 48.7; 95% CI, 8.81-269; P<0.01), intermediate attenuation (OR, 19.3; 95% CI, 4.96-75.4;...Continue Reading
References
Nov 15, 1989·Journal of the American College of Cardiology·J C KaskiD Hackett
Apr 12, 1973·The New England Journal of Medicine·P B OlivaR G Pluss
Sep 1, 1995·American Heart Journal·J KoyamaK Miyatake
Feb 1, 1994·Journal of the American College of Cardiology·M YamagishiS E Nissen
Feb 1, 1996·The Journal of Clinical Investigation·H ShimokawaA Takeshita
Jun 1, 1996·Journal of the American College of Cardiology·T NishiokaR J Siegel
Feb 6, 1999·Journal of the American College of Cardiology·H SuzukiH Yamaguchi
Aug 10, 2000·Journal of the American College of Cardiology·Y MiyaoH Yasue
Aug 31, 2000·American Heart Journal·M K HongS J Park
Aug 15, 2002·American Heart Journal·Chao-Hung WangWen-Jin Cherng
Dec 24, 2003·Circulation·Stephan AchenbachThomas J Brady
Apr 6, 2004·Journal of the American College of Cardiology·Alexander W LeberPeter Boekstegers
Mar 8, 2005·European Radiology·Filippo CademartiriPim J de Feyter
Aug 2, 2005·Journal of the American College of Cardiology·Gilbert L RaffJames A Goldstein
Jun 26, 2007·Circulation Journal : Official Journal of the Japanese Circulation Society·Teruhiko ItohHirofumi Yasue
Jul 31, 2007·Journal of the American College of Cardiology·Sadako MotoyamaJagat Narula
Aug 9, 2008·Journal of the American College of Cardiology·Peter OngUdo Sechtem
May 20, 2009·International Journal of Cardiology·Young Joon HongJung Chaee Kang
Sep 1, 2009·International Journal of Cardiology·Yoshinobu MorikawaYoshihiko Saito
Dec 25, 2009·Circulation. Cardiovascular Interventions·Hitoshi NakagawaHirofumi Yasue
Jul 31, 2010·Circulation Journal : Official Journal of the Japanese Circulation Society·UNKNOWN JCS Joint Working Group
Dec 8, 2010·Circulation·Ali YilmazUdo Sechtem
Jan 8, 2011·Journal of the American College of Cardiology·Peter OngUdo Sechtem
Feb 26, 2011·The American Journal of Cardiology·Tsuyoshi ItoTakahiko Suzuki
Citations
Apr 17, 2014·TheScientificWorldJournal·Heng-Jung HsuMing-Jui Hung
Mar 11, 2015·International Journal of Cardiology·Tsuyoshi ItoNobuyuki Ohte
Jun 19, 2015·Circulation Journal : Official Journal of the Japanese Circulation Society·Peter OngUdo Sechtem
Jan 3, 2015·International Journal of Cardiology·Rex N MacAlpin
Dec 24, 2013·International Journal of Cardiology·Natale Daniele BrunettiMatteo Di Biase
May 4, 2016·The International Journal of Cardiovascular Imaging·Song Soo KimArthur E Stillman
Jun 1, 2016·Case Reports in Cardiology·Nuray Kahraman AyÖmer Goktekin
Jul 7, 2016·European Radiology·Eun-Ju KangYeonyee Elizabeth Yoon
Jul 20, 2016·International Journal of Cardiology·Tsuyoshi ItoNobuyuki Ohte
Aug 31, 2016·International Journal of Cardiology·Min Seok OhSeung-Hyuk Choi
Nov 19, 2014·Coronary Artery Disease·Peter OngJuan Carlos Kaski
Sep 20, 2012·Internal Medicine·Turgut KarabagEmrah Kucuk
Nov 23, 2017·Cardiology·Cai De JinVictor Serebruany
Apr 18, 2019·Korean Journal of Radiology : Official Journal of the Korean Radiological Society·Jiesuck ParkDae Won Sohn
Jun 10, 2020·Current Problems in Diagnostic Radiology·Joanna G EscalonDaniel Vargas