In vivo assessment of spinal cord elasticity using shear wave ultrasound in dogs

Journal of Neurosurgery. Spine
Amro Al-HabibTariq Alzahrani

Abstract

Evaluation of living tissue elasticity has wide applications in disease characterization and prognosis prediction. Few previous ex vivo attempts have been made to characterize spinal cord elasticity (SCE). Recently, tissue elasticity assessment has been clinically feasible using ultrasound shear wave elastography (SWE). The current study aims to characterize SCE in healthy dogs, in vivo, utilizing SWE, and to address SCE changes during compression. Ten Greyhound dogs (mean age 14 months; mean weight 14.3 kg) were anesthetized and tracheally intubated, with hemodynamic and neurological monitoring. A 3-level, midcervical laminectomy was performed. SCE was assessed at baseline. Next, 8- and 13-mm balloon compressions were sequentially applied ventral to the spinal cord. The mean SCE was 18.5 ± 7 kPa. Elasticity of the central canal, pia mater, and dura mater were 21.7 ± 9.6 kPa, 26.1 ± 14.8 kPa, and 63.2 ± 11.5 kPa, respectively. As expected, the spinal cord demonstrated less elasticity than the dura mater (p < 0.0001) and pia mater (trend toward significance p = 0.08). Notably, the 13-mm balloon compression resulted in a stiffer spinal cord than at baseline (233 ± 73 kPa versus 18.5 ± 7 kPa, p < 0.0001) and 8-mm balloon compressi...Continue Reading

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Citations

Jun 29, 2021·Clinical Neurology and Neurosurgery·Ghaida AlawajiAbdulrazag Ajlan
Aug 21, 2021·Journal of Neurosurgery. Spine·Amro Al-HabibAbdulrazag Ajlan

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Methods Mentioned

BETA
biopsies
surgical resections
dissection
imaging technique
imaging techniques

Software Mentioned

SPSS
Statistical Package for Social Science Software (

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