PMID: 2503633May 1, 1989Paper

In vivo biliary function in the adult rat: the effect of parenteral glucose and amino acids

JPEN. Journal of Parenteral and Enteral Nutrition
A RiveraE Catarau

Abstract

Parenteral glucose and glucose-amino acid mixtures are used in the nutritional support of infants, children, and adults when enteral feedings are precluded for any reason. During the first week of such nutritional support, the total energy intakes are generally low and glucose and electrolytes are the only nutrients provided. To assess the effects of such "hypocaloric" regimens, we determined the hepatic responses to parenteral infusions of either glucose or glucose-amino acid mixtures in rats. Further, to illustrate the magnitude of these changes in comparison to normally fed animals, we included a group of sham-operated, chow-fed rats. Bile flow, biliary bile acid output, bile osmolarity, serum bile acids, and plasma amino acids were measured in adult rats following 5 days of the respective dietary regimens. Liver histology was also assessed. Bile acid output, but not bile flow, was significantly decreased by the infusion of glucose compared to glucose-amino acid mixtures. However, in comparison to the chow-fed rats, bile acid output was significantly reduced in both groups of parenterally fed animals, whereas bile flow was significantly reduced only in the glucose-infused animals. Plasma amino acids were markedly different b...Continue Reading

References

Jun 1, 1979·JAMA : the Journal of the American Medical Association·K D LindorM A Hirschkorn
May 1, 1979·JPEN. Journal of Parenteral and Enteral Nutrition·Y HiraiN Kuwabara
Mar 1, 1977·The Journal of Pediatrics·J BernsteinK P Heidelberger
Apr 1, 1978·Archives of Surgery·G F SheldonR Sanders
Feb 1, 1975·The Journal of Pediatrics·R Rager, M J Finegold
Jun 1, 1975·Journal of Pediatric Surgery·R J Touloukian, J H Seashore
Apr 1, 1987·The Journal of Nutrition·L VillalonI M Yousef
Jan 1, 1985·JPEN. Journal of Parenteral and Enteral Nutrition·F M MartinsL Lindmark
Jul 1, 1985·JPEN. Journal of Parenteral and Enteral Nutrition·J Bhatia, D K Rassin
Aug 1, 1985·Archives of Disease in Childhood·H M BergerJ J Calame
Oct 1, 1985·Journal of Pediatric Gastroenterology and Nutrition·I ZahaviD G Gall
Mar 1, 1972·Archives of Surgery·E SteigerS J Dudrick
Apr 1, 1974·Canadian Journal of Physiology and Pharmacology·C D Klaassen
Jan 1, 1984·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·M F GrahamL N Louis
Jan 1, 1981·JPEN. Journal of Parenteral and Enteral Nutrition·R A VileisisC E Hunt
Mar 1, 1982·The Journal of Surgical Research·Z GimmonJ E Fischer

❮ Previous
Next ❯

Citations

May 5, 1998·Journal of Hepatology·H A GielkensA A Masclee
Jan 1, 1992·Scandinavian Journal of Gastroenterology. Supplement·S Y de BoerC B Lamers
May 1, 1991·JPEN. Journal of Parenteral and Enteral Nutrition·D J SweenyR B Diasio
May 1, 1991·JPEN. Journal of Parenteral and Enteral Nutrition·F GuertinB Tuchweber
Mar 1, 1993·JPEN. Journal of Parenteral and Enteral Nutrition·J M CulebrasJ Gonzalez-Gallego
Nov 1, 1991·JPEN. Journal of Parenteral and Enteral Nutrition·Z J ShuT H Zhang
Jul 1, 1991·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·J J MarinG R Villanueva
Aug 15, 2002·American Journal of Physiology. Cell Physiology·Anatoly I MasyukNicholas F LaRusso

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.