In vivo comparison of scanning technique and wavelength in laser Doppler perfusion imaging: measurement in knee ligaments of adult rabbits

Medical & Biological Engineering & Computing
Kevin ForresterR Bray

Abstract

At present, there are only two laser Doppler perfusion imaging systems (LDIs) manufactured for medical applications: a 'stepwise' and a 'continuous' scanning LDI. The stepwise scanning LDI has previously been investigated and compared with coloured microsphere determined standardised flow. The continuous scanning LDI is investigated and compared with the stepwise scanning LDI for its ability to measure in vivo, hypoaemic, ligament tissue blood flow changes. The continuous scanning system was supplied with two lasers, red and near infrared (NIR), allowing for additional assessment of the effect of wavelength on imaging ligament perfusion. Perfusion images were obtained from surgically exposed rabbit medial collateral ligaments (MCL). Continuous and stepwise LDI scans were compared using correlation and linear regression analysis of image. averages and standard deviations. Using the same method of analysis, LDI measurements using red and NIR lasers indicated a high degree of correlation, at least over the ranges of perfusion assessed, indicating that red and NIR lasers measure similar regions of flow in the rabbit MCL. These experiments confirm that both LDI techniques provide a valid in vivo measure of dynamic changes in connect...Continue Reading

References

Jan 1, 1978·IEEE Transactions on Bio-medical Engineering·D Watkins, G A Holloway
May 1, 1991·Journal of Biomedical Engineering·T J Essex, P O Byrne
Nov 1, 1990·Journal of Medical Engineering & Technology·N J BarnettS J Pettinger
Aug 1, 1986·Journal of Applied Physiology·G J SmitsJ H Lombard
Jul 1, 1984·Medical & Biological Engineering & Computing·G E Nilsson
Jan 1, 1980·IEEE Transactions on Bio-medical Engineering·G E NilssonP A Obert
Oct 1, 1980·IEEE Transactions on Bio-medical Engineering·G E NilssonP A Oberg
Apr 1, 1993·IEEE Transactions on Bio-medical Engineering·K WårdellG E Nilsson
May 1, 1993·Medical & Biological Engineering & Computing·A Jakobsson, G E Nilsson
May 1, 1996·Medical & Biological Engineering & Computing·R BrayW R Ferrell

❮ Previous
Next ❯

Citations

Jan 1, 2003·Medical & Biological Engineering & Computing·K R ForresterR C Bray
Apr 6, 2012·Medical & Biological Engineering & Computing·Kausik BasakPranab Kumar Dutta
Apr 23, 2003·Burns : Journal of the International Society for Burn Injuries·Robert BrayRobert Lindsay
Nov 5, 2003·Proceedings of the National Academy of Sciences of the United States of America·L R HirschJ L West
Sep 1, 2005·Burns : Journal of the International Society for Burn Injuries·C J StewartR C Bray
Sep 3, 2011·Microcirculation : the Official Journal of the Microcirculatory Society, Inc·Matthieu Roustit, Jean-Luc Cracowski
Nov 13, 2004·IEEE Transactions on Bio-medical Engineering·Kevin R ForresterRobert C Bray
May 4, 2005·The International Journal of Lower Extremity Wounds·Faisel Khan, David J Newton
Sep 2, 2003·Lasers in Surgery and Medicine·K R ForresterR C Bray
Aug 25, 1999·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·R C ChanR F Zernicke
Sep 11, 2007·Physiological Measurement·Hans Knotzer, Walter R Hasibeder
Jan 18, 2005·World Journal of Surgery·Bishara S AtiyehShady N Hayek
Jun 10, 2000·Physiological Measurement·D P Kernick, A C Shore
Mar 15, 2001·Journal of Applied Physiology·R C ShymkiwR C Bray

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

IEEE Transactions on Bio-medical Engineering
Kevin ForresterRobert C Bray
Burns : Journal of the International Society for Burn Injuries
Robert C BrayRobert Lindsay
© 2022 Meta ULC. All rights reserved