In vivo confocal microscopy after herpes keratitis

Cornea
Maria E RosenbergMinna H Vesaluoma

Abstract

To describe the confocal microscopic findings, with special reference to corneal subbasal nerves, after herpes simplex virus (HSV) keratitis. In this study, 16 HSV eyes and 14 contralateral eyes of 16 patients, diagnosed with unilateral HSV keratitis 1-12 months earlier by the presence of dendritic corneal ulceration or microbiologic confirmation, were examined by in vivo confocal microscopy for evaluation of corneal morphology. Herpes simplex virus eyes: In 2 eyes the surface epithelial cells appeared large, and no abnormalities were observed in the basal epithelial cells. In 2 eyes subbasal nerve fiber bundles were completely absent, in 3 eyes there was a reduced number of long nerve fiber bundles, and in 11 eyes the subbasal nerve plexus appeared normal. In 10 corneas, highly reflective dendritic structures were found at the level of the basal epithelial cells. Frequently these structures were found in the vicinity of stromal fibrosis. Areas with increased abnormal extracellular matrix were found in 11 eyes. Stromal nerves were not visualized in all corneas, but appeared normal when observed. Contralateral eyes: No abnormalities were observed in the epithelium. All corneas presented with a normal subbasal nerve plexus, but i...Continue Reading

References

Jan 1, 1987·Current Eye Research·P A Asbell, T Kamenar
Jun 1, 1982·Ophthalmology·T E GilletteJ V Greiner
Dec 1, 1995·The Journal of Allergy and Clinical Immunology·A AsahinaR D Granstein
Mar 25, 1999·Cornea·E J Holland, G S Schwartz
Aug 7, 1999·Progress in Retinal and Eye Research·M Böhnke, B R Masters
Nov 27, 1999·The British Journal of Ophthalmology·L KuffováM Filipec

❮ Previous
Next ❯

Citations

Aug 24, 2004·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·S KnappeR F Guthoff
Apr 28, 2005·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Andrey ZhivovRudolf Guthoff
Aug 31, 2006·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Oliver StachsRudolf Guthoff
May 22, 2010·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Elisabeth M MessmerAnselm Kampik
Jan 27, 2011·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jiaxu HongYimin Li
Aug 11, 2011·Japanese Journal of Ophthalmology·Daisuke NagasatoMurat Dogru
Feb 26, 2008·International Ophthalmology·Qi-Hua LeJian-Jiang Xu
Apr 17, 2003·Experimental Eye Research·Linda J MüllerTimo M T Tervo
Jul 11, 2003·Progress in Retinal and Eye Research·Timo Tervo, Jukka Moilanen
Mar 19, 2003·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·Laura Oliveira-Soto, Nathan Efron
Jul 15, 2005·Cornea·Jay C ErieWilliam M Bourne
Mar 26, 2008·Cornea·André Alexandre Dosso, Elisabeth Rungger-Brändle
Jan 7, 2009·International Ophthalmology Clinics·Mohammad H Dastjerdi, Reza Dana
Jan 25, 2003·The British Journal of Ophthalmology·I JalbertM Coroneo
May 25, 2013·Investigative Ophthalmology & Visual Science·Maria Soledad CortinaHaydee E P Bazan
Jun 1, 2008·Clinical Ophthalmology·Mitra TavakoliRayaz A Malik
Jun 15, 2007·Current Opinion in Ophthalmology·Jasmeet S DhaliwalAuguste Gy Chiou
Feb 14, 2009·The Ocular Surface·Antoine LabbéChristophe Baudouin
Dec 20, 2011·Ophthalmology·Andrea LeonardiIva Fregona
Nov 1, 2011·Ophthalmology·Toine HillenaarLies Remeijer
Sep 21, 2010·Contact Lens & Anterior Eye : the Journal of the British Contact Lens Association·M TavakoliR A Malik
Feb 16, 2010·Journal français d'ophtalmologie·R Tahiri Joutei HassaniC Baudouin
Nov 13, 2007·Seminars in Cell & Developmental Biology·James V Jester
Apr 10, 2007·Ophthalmology·Eric E GabisonThanh Hoang-Xuan
Mar 10, 2016·Seminars in Ophthalmology·Sunali Goyal, Pedram Hamrah
Dec 4, 2003·Acta Ophthalmologica Scandinavica·Einar StefánssonAnders Heijl
May 19, 2012·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Mitra TavakoliRayaz A Malik

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.