In Vivo Measurement of the Human Vitreous Chamber Volume Using Computed Tomography Imaging of 100 Eyes

Translational Vision Science & Technology
Ariel M AzhdamShoaib Ugradar

Abstract

To accurately measure the vitreous chamber volume (VCV) in humans using high-resolution computed tomography (CT) scanning techniques combined with three-dimensional analysis software. Potential relationships between age, axial length, and VCVs were also explored. In this retrospective study, the eyes of 100 healthy individuals were studied. Scans were acquired during clinical care and did not show any signs of orbital pathology. Exclusion criteria included any ocular history. CT scans were acquired with a slice thickness of 0.7 mm, and volumetric analysis was carried out using the MIMICS image analysis software version 19.0 (Materialise, Leuven, Belgium). The final sample included 100 eyes from 50 patients (30 women, 20 men). The mean age was 48.67 ± 20.72 years, and the age range was 18 to 91 years. The mean VCV was 4.649.99 ± 0.426.54 mm3 for women and 4.969.0 ± 0.465.20 mm3 for men. We found a significant correlation between age and VCV (P < 0.001), axial length and VCV (P < 0.001), and age and axial length (P < 0.005). The VCV appears to be greater than the current consensus suggests. This work also suggests that the VCV is associated with age and axial length, indicating that it is dynamic and may change throughout adultho...Continue Reading

References

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Jul 31, 2013·Biomechanics and Modeling in Mechanobiology·Massimo A FazioJ Crawford Downs

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Citations

Nov 4, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Juliana Moreira de SantanaRodrigo Pessoa Cavalcanti Lira
Mar 11, 2020·Progress in Retinal and Eye Research·J Sebag
May 1, 2021·Investigative Ophthalmology & Visual Science·Daniel RuminskiIreneusz Grulkowski
Jun 9, 2021·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Andrea AllmendingerClaudia Mueller
Jan 5, 2022·Translational Vision Science & Technology·Xiaoxuan LiuAlastair K Denniston

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Software Mentioned

SPSS
MIMICS

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