In-vivo microstructural anatomy of beta-zone parapapillary atrophy in glaucoma

Investigative Ophthalmology & Visual Science
Sung Chul ParkRobert Ritch

Abstract

To assess the microstructural anatomy of clinical β-zone parapapillary atrophy (βPPA) by using Fourier-domain optical coherence tomography (FD-OCT). Color photographs and horizontal cross-sectional FD-OCT images of the optic disc and parapapillary retina were obtained in 24 eyes (24 patients with glaucoma or suspected glaucoma) with βPPA. The distances between the temporal disc margin and parapapillary landmarks (clinical βPPA margin and the edges of the retinal pigment epithelium [RPE], Bruch's membrane [BM], and the photoreceptor inner/outer segment [IS/OS] junction) were measured in 5 equally spaced horizontal meridians (total, 120 meridians). The mean age was 56 ± 13 (SD) years. In the five meridians, the mean distances from the temporal disc margin to the temporal βPPA margin and the edges of RPE, BM, and the IS/OS junction were 388 ± 173, 371 ± 174, 214 ± 204, and 502 ± 167 μm, respectively. The RPE edge corresponded to the βPPA margin in 78 (65%) of 120 meridians and ended within the βPPA in 42 (35%) of 120 meridians. The BM edge corresponded to the RPE edge in 13 (11%) of 120 meridians and was closer to the disc in 107 (89%) of 120 meridians. The disc margin corresponded to the BM edge in 20 (17%) of 120 meridians and t...Continue Reading

Citations

Jul 16, 2013·Japanese Journal of Ophthalmology·Young Hoon HwangJoo Hwa Lee
Oct 25, 2012·PloS One·Jost B JonasSonghomitra Panda-Jonas
Apr 21, 2017·Retina·Jost B JonasKyoko Ohno-Matsui
Jul 20, 2018·Investigative Ophthalmology & Visual Science·Qi ZhangJost B Jonas
Mar 1, 2012·Asia-Pacific Journal of Ophthalmology·Carlos Gustavo De MoraesRobert Ritch
Oct 3, 2017·European Journal of Ophthalmology·Antonio LongoMichele Reibaldi
Sep 12, 2014·Ophthalmology·Eleonore SavatovskyUNKNOWN Ocular Hypertension Treatment Study

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