In vivo morphological characterisation of skin by MRI micro-imaging methods

Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
Fakhereh Mirrashed, Jonathan C Sharp

Abstract

Quantitative assessments in skin layers using images obtained with standard magnetic resonance imaging (MRI) sequences are limited, since the stratum corneum and dermis, the layers of most clinical interest, have low signal due to their short spin-spin relaxation, T2. In the present work, different methods of MRI contrast, such as magnetisation transfer contrast (MTC), T1-weighting (where T1 is spin-lattice relaxation time), T2*-weighting (where T2* is the combination of T2 and magnetic field in-homogeneity effect) and chemical shift, were used. These techniques were combined with high-resolution MRI. We found that skin is a very MT active tissue, and MTC provides data enabling the evaluation of how the tissue in skin layers interacts with the interstitial fluids. Details obtained from high-resolution high-quality in vivo skin images with different contrast allowed for differentiation of skin layers, sub-layers and excellent correlation of MR data with known histological features and water constituent of skin layers. Combining MT and other MRI data employing other contrast mechanisms provides a superior non-invasive in vivo technique for visualisation and also quantitative assessment of the constituents of the stratum corneum, ...Continue Reading

Citations

Apr 24, 2007·AJR. American Journal of Roentgenology·Hubert GuflerWigbert S Rau
Jul 27, 2012·Future Oncology·Verena Ahlgrimm-SiessRainer Hofmann-Wellenhof
Jun 21, 2005·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Ralph P BraunJean-Paul Vallée
Jul 10, 2010·Journal of Biomedical Optics·Zhun XuLihong V Wang
Nov 11, 2008·Physics in Medicine and Biology·S H ChungB J Tromberg
Jan 30, 2008·Journal of Pharmaceutical Sciences·I RodríguezJ Ruíz-Cabello
Jul 14, 2010·European Journal of Radiology·Nicolas SansJean-Jacques Railhac
Nov 1, 2006·NMR in Biomedicine·Jacques BittounLuc Darrasse
May 24, 2007·Journal of Magnetic Resonance Imaging : JMRI·Mary Preston McDougall, Steven M Wright
Feb 24, 2011·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Louise Smith, Sheila Macneil
Jun 25, 2010·International Journal of Cosmetic Science·A J Byrne
Jun 20, 2012·Journal of Biophotonics·Susan M Daly, Martin J Leahy
Jan 22, 2013·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Laura CalzolariSebastien Aubry
May 12, 2010·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Noriaki NakagawaShingo Sakai
Feb 11, 2010·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Joëlle K BarralDwight G Nishimura
Nov 1, 2005·Journal of Pharmacological and Toxicological Methods·C I WrightR Draijer
Jul 15, 2015·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Matthew J BudakIan A Zealley
Jul 17, 2015·Bioelectromagnetics·Maxim ZhadobovEvgeny E Fesenko
Jun 30, 2015·Early Human Development·Akio IshiguroMasanori Tamura
Feb 1, 2017·IEEE Transactions on Bio-medical Engineering·Neha BajwaZachary D Taylor
Oct 12, 2007·Bioelectromagnetics·S I AlekseevM C Ziskin
Jul 20, 2010·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Rakesh Sharma
Apr 13, 2007·Bioelectromagnetics·S I Alekseev, M C Ziskin
Aug 16, 2019·Cancer Investigation·Ashok SharmaMoganty Raja Rajeswari
Oct 23, 2020·International Journal of Pharmaceutics·Małgorzata TarnowskaMarie-Alexandrine Bolzinger
Feb 22, 2021·Drug Delivery and Translational Research·Pia KaiserMaike Windbergs
Jan 18, 2018·Journal of Pharmaceutical Sciences·Michael R Turner, Sathy V Balu-Iyer
Jun 3, 2021·Sensors·Jiarui WangEmma Pickwell-MacPherson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine
H K SongJ Ma
BMJ : British Medical Journal
Abi Berger
Annual Review of Biomedical Engineering
Michal Neeman, Hagit Dafni
Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
Fakhereh Mirrashed, Jonathan C Sharp
© 2022 Meta ULC. All rights reserved