In vivo oxygen, temperature and pH dynamics in the female reproductive tract and their importance in human conception: a systematic review

Human Reproduction Update
Ka Ying Bonnie NgYing Cheong

Abstract

Despite advances in ART, implantation and pregnancy rates per embryo transfer still remain low. IVF laboratories strive to ensure that the process of handling gametes in vitro closely mimics the in vivo environment. However, there remains a lack of knowledge regarding the in vivo regulation and dynamic variation in biophysical parameters such as oxygen concentration, pH and temperature within the reproductive tract. To undertake a systematic review of the current understanding of the physico-chemical parameters of oxygen tension (pO2), pH and temperature within the female reproductive tract, and their potential implications in clinical and pathological processes related to fertility and those pertaining to limited reproductive capacity. A comprehensive literature search was performed using electronic databases including Medline, Embase, Cochrane Library and Pubmed to identify original and review articles addressing the biophysical parameters (pO2, pH and temperature) in the female reproductive tract of any species. The search included all studies published between 1946 and November 2015. Search terms included 'oxygen', 'pH', 'hydrogen ion concentration', 'acid base' and others terms. We also used special features and truncation...Continue Reading

Associated Clinical Trials

References

Mar 1, 1975·Theriogenology·E C Mather
Oct 1, 1978·The Journal of Experimental Zoology·P Quinn, G M Harlow
Nov 1, 1976·Fertility and Sterility·D H MaasL Mastroianni
Feb 15, 1976·American Journal of Obstetrics and Gynecology·H J BenoitC A Woolever
Jan 1, 1976·Advances in Experimental Medicine and Biology·K Kunze
Nov 19, 1992·European Journal of Obstetrics, Gynecology, and Reproductive Biology·A R MartinezP G Hompes
Jan 1, 1992·Molecular Reproduction and Development·Y UmaokaT Mori
Apr 1, 1992·Alcoholism, Clinical and Experimental Research·J A Mitchell, B R Van Kainen
Nov 17, 1990·BMJ : British Medical Journal·D J Barker
Oct 1, 1988·Human Reproduction·W Eggert-KruseD Petzoldt
May 1, 1987·Journal of Reproduction and Fertility·P V BaggerM D Christiansen
Apr 1, 1974·Endocrinology·R ResnikG Meschia
Mar 1, 1972·Journal of Reproduction and Fertility·R ShalgiN Soferman
Jan 1, 1972·American Journal of Obstetrics and Gynecology·F PeetersJ van Cutsem
Oct 1, 1971·Journal of Animal Science·A IritaniN L VanDemark
Nov 15, 1970·American Journal of Obstetrics and Gynecology·R M AbramsD H Barron
Sep 1, 1984·JOGN Nursing; Journal of Obstetric, Gynecologic, and Neonatal Nursing·J T Samples, R M Abrams
Jan 1, 1983·Advances in Experimental Medicine and Biology·J A MitchellH Goldman
Sep 1, 1980·Fertility and Sterility·P M Zavos, M R Cohen
Sep 1, 1981·Journal of Reproduction and Fertility·R E HammerJ A Mitchell
Sep 1, 1980·Journal of Reproduction and Fertility·J GrinstedA G Byskov
Jul 1, 1980·Annals of Human Biology·C R Bangham, J M Sacherer
Oct 13, 1995·The Journal of Biological Chemistry·Y ZhaoJ M Baltz
Aug 1, 1995·British Journal of Obstetrics and Gynaecology·H McNamara, N Johnson
Mar 1, 1995·Obstetrics and Gynecology·I Z GlatsteinM D Hornstein
Apr 1, 1994·Comparative Biochemistry and Physiology. Comparative Physiology·D L Kaufman, J A Mitchell
Nov 1, 1993·Journal of Reproduction and Fertility·B Fischer, B D Bavister
Jul 1, 1993·Free Radical Biology & Medicine·Y GotoM Nakano
Apr 1, 1996·Fertility and Sterility·M M IjlandH J Hoogland
Mar 1, 1996·Medical Engineering & Physics·Z McCreeshW G Scanlon

❮ Previous
Next ❯

Citations

Mar 2, 2018·Reproduction : the Official Journal of the Society for the Study of Fertility·Stefania MuzzachiElena Ciani
Nov 6, 2018·Molecular Human Reproduction·S J CalvertA A Pacey
Jan 11, 2019·The Journal of Reproduction and Development·Fernando López-Gatius, Ronald H F Hunter
Oct 22, 2019·Human Reproduction·R Ya SmithT E DeCoursey
Sep 12, 2019·Physiological Reviews·S F Pedersen, L Counillon
Dec 10, 2019·Molecular Human Reproduction·J SantiagoJ V Silva
Apr 23, 2020·Reproduction, Fertility, and Development·Jilong ZhouYi-Liang Miao
Apr 29, 2020·Zygote : the Biology of Gametes and Early Embryos·M JamilR Cadi
Aug 28, 2020·Journal of Assisted Reproduction and Genetics·Emily A SeidlerD J Needleman
Mar 4, 2020·Journal of Assisted Reproduction and Genetics·Nicolas GatimelRoger D Léandri
May 8, 2020·High-throughput·Rossella TomaiuoloValeria D'Argenio
May 10, 2020·Animals : an Open Access Journal From MDPI·Ximo Garcia-DominguezFrancisco Marco-Jiménez
Sep 10, 2019·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Tharaka Darshana WijerathneKyu Pil Lee
Sep 24, 2019·Zygote : the Biology of Gametes and Early Embryos·R Sciorio, G D Smith
Jul 24, 2018·Veterinary World·Abhishek Kumar MishraRajesh Nigam
Jan 27, 2019·Nature Reviews. Disease Primers·Cynthia M FarquharJacky Boivin
Dec 24, 2018·Human Reproduction·N De MunckG Verheyen
Feb 23, 2020·Acta Obstetricia Et Gynecologica Scandinavica·Ronald H F Hunter, Fernando López-Gatius
Oct 1, 2020·International Journal of Molecular Sciences·Ximo Garcia-DominguezFrancisco Marco-Jiménez
Dec 22, 2019·Antioxidants & Redox Signaling·Lucia von MengdenJohan Smitz
Nov 20, 2020·International Journal of Molecular Sciences·Francisco Marco-JiménezJosé S Vicente
Oct 30, 2020·Antioxidants & Redox Signaling·Jing Lin, Ling Wang
Jul 19, 2020·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Ronald H F Hunter, Fernando López-Gatius
Feb 6, 2021·Scientific Reports·Octavio López-AlborsFrancisco Alberto García-Vázquez
Mar 17, 2020·Reproductive Biomedicine Online·Emily A WaltersJason E Swain
Feb 12, 2021·Animals : an Open Access Journal From MDPI·Fabio De RensisFernando López-Gatius
Nov 21, 2020·Nature Reviews. Urology·Huafeng WangJean-Ju Chung
Apr 9, 2021·Advanced Drug Delivery Reviews·Rachel E Young, Dan Dongeun Huh
Oct 15, 2020·Cryobiology·Ximo Garcia-DominguezFrancisco Marco-Jiménez
May 1, 2021·International Journal of Molecular Sciences·Marina Ramal-SanchezBarbara Barboni
May 1, 2021·Nutrients·Michał CiebieraMohamed Ali
Apr 14, 2018·Chemical Reviews·Nicholas J BarrowsMariano A Garcia-Blanco

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Human Reproduction Update
Christopher De Jonge
Journal of Assisted Reproduction and Genetics
Mohammad EzzatiBruce R Carr
The Cochrane Database of Systematic Reviews
Stephan BontekoeSebastiaan Mastenbroek
© 2022 Meta ULC. All rights reserved