In vivo performance of a visible wavelength optical sensor for monitoring intestinal perfusion and oxygenation

Journal of Biomedical Optics
Mitchell B RobinsonGerard L Coté

Abstract

Traumatic injury resulting in hemorrhage is a prevalent cause of death worldwide. The current standard of care for trauma patients is to restore hemostasis by controlling bleeding and administering intravenous volume resuscitation. Adequate resuscitation to restore tissue blood flow and oxygenation is critical within the first hours following admission to assess severity and avoid complications. However, current clinical methods for guiding resuscitation are not sensitive or specific enough to adequately understand the patient condition. To better address the shortcomings of the current methods, an approach to monitor intestinal perfusion and oxygenation using a multiwavelength (470, 560, and 630 nm) optical sensor has been developed based on photoplethysmography and reflectance spectroscopy. Specifically, two sensors were developed using three wavelengths to measure relative changes in the small intestine. Using vessel occlusion, systemic changes in oxygenation input, and induction of hemorrhagic shock, the capabilities and sensitivity of the sensor were explored in vivo. Pulsatile and nonpulsatile components of the red, blue, and green wavelength signals were analyzed for all three protocols (occlusion, systemic oxygenation c...Continue Reading

References

Jan 1, 1977·Medical & Biological Engineering & Computing·J WeinmannG Raviv
Sep 1, 1991·Medical & Biological Engineering & Computing·Y ShimadaS Takatani
Aug 1, 1981·Clinical Physics and Physiological Measurement : an Official Journal of the Hospital Physicists' Association, Deutsche Gesellschaft Für Medizinische Physik and the European Federation of Organisations for Medical Physics·J A NijboerH F Mahieu
Mar 1, 1996·The Journal of Surgical Research·S A Skinner, P E O'Brien
Aug 7, 1999·Langenbeck's Archives of Surgery·U Haglund, D Bergqvist
Dec 22, 1999·Lasers in Surgery and Medicine·J A Viator, S A Prahl
Aug 18, 2000·The Journal of Surgical Research·P J MathesonR N Garrison
Nov 22, 2000·The Journal of Trauma·L N DiebelS A Dulchavsky
Aug 7, 2002·Critical Care Medicine·Jack W Kern, William C Shoemaker
Oct 30, 2004·The Journal of Trauma·Samuel A TishermanRonald Simon
Jul 13, 2006·The Journal of Trauma·Frederick A MooreUNKNOWN Inflammation and the Host Response to Injury Collaborative Research Program
Jan 12, 2007·The Journal of Trauma·Stephen M CohnUNKNOWN StO2 in Trauma Patients Trial Investigators
Oct 20, 2007·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society·Y MendelsonG Comtois
Dec 6, 2007·Anesthesia and Analgesia·Paul D Mannheimer
Jun 9, 2009·European Journal of Radiology·Carmel G CroninJoseph M Murphy
Aug 22, 2009·Blood Reviews·Philip C Spinella, John B Holcomb
Dec 5, 2009·The Journal of Surgical Research·Shinil K ShahCharles S Cox
May 31, 2011·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Annette PlüddemannChristopher Price
Apr 24, 2013·The Journal of Trauma and Acute Care Surgery·UNKNOWN ATLS SubcommitteeUNKNOWN International ATLS working group
Aug 15, 2013·Journal of Biomedical Optics·Tony J AklGerard L Coté
Feb 25, 2014·Critical Care Medicine·Guillaume TachonJacques Duranteau
May 23, 2015·Scientific Reports·Alexei A KamshilinRoman V Romashko
Dec 15, 2015·Critical Care : the Official Journal of the Critical Care Forum·Chun-Yu WuUNKNOWN NTUH Center of Microcirculation Medical Research
Nov 8, 2016·Shock·Lorilee S L ArakakiKenneth A Schenkman
Apr 15, 2017·Shock·Basilia Zingarelli, Jennifer M Kaplan
Sep 1, 2017·Biomedical Optics Express·Mitchell B RobinsonGerard L Coté

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Imaging in CNS

Here is the latest research on cell imaging and imaging modalities, including light-sheet microscopy, in the central nervous system.

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

Related Papers

Journal of Biomedical Optics
Tony J AklGerard L Coté
Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Zaibaa PatelP A Kyriacou
JAMA : the Journal of the American Medical Association
I MANDELBAUM, W H BURNS
© 2022 Meta ULC. All rights reserved