PMID: 3214746Sep 1, 1988Paper

In vivo properties of neurons of the precruciate cortex of cats

Brain Research Bulletin
N Berthier, C D Woody

Abstract

The electrical properties of 409 cells of the precruciate cortex of cats were measured intracellularly, in vivo. Resting potentials (RP) averaged -54 +/- 11 mV (SD), and action potentials (AP) of up to 80 mV were found. The magnitude of RP was correlated with the size of AP recorded. Input resistance averaged 8.4 +/- 8.0 megohms (n = 180 cells) and was uncorrelated with AP or RP. There were no significant differences in the above electrical properties between HRP-identified layer V pyramidal cells (n = 56) and unidentified cells (n = 353). However, within layer V pyramidal cells, the size of the soma was relatable to input resistance. Comparisons of present in vivo data with in vitro data obtained by other investigators from cells of the same region, type and species indicate that resting potentials are more positive in vivo than in vitro, but that critical firing thresholds are the same. Injections of ramp depolarizing currents in 118 unidentified cells disclosed 82% simple (no or minimal accommodation) responses. 18% ceiling (small accommodation) responses, and no minimal gradient (large accommodation or injury) responses. This finding was similar to that found in layer V pyramidal cells in vitro.

References

Jun 6, 1986·Neuroscience Letters·J V Halliwell
May 1, 1971·The Journal of Physiology·K KrnjevićL Renaud
Jul 1, 1968·Experimental Neurology·D A Prince
Oct 28, 1982·Brain Research·J V Halliwell, P R Adams
Jan 1, 1984·Annual Review of Physiology·B Sakmann, E Neher
Sep 1, 1982·The Journal of Physiology·P R AdamsA Constanti
Nov 1, 1982·The Journal of Physiology·I S Kass, P Lipton
Nov 28, 1956·The Journal of Physiology·K FRANK, M G FUORTES
Jan 1, 1956·Quarterly Journal of Experimental Physiology and Cognate Medical Sciences·C G PHILLIPS

❮ Previous
Next ❯

Citations

Nov 18, 2005·Journal of Physiology, Paris·Michael Rudolph, Alain Destexhe
Sep 3, 2003·Nature Reviews. Neuroscience·Alain DestexheDenis Paré

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.