In vivo rectal wall measurements during HDR prostate brachytherapy with MOSkin dosimeters integrated on a trans-rectal US probe: Comparison with planned and reconstructed doses

Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology
M CarraraEmanuele Pignoli

Abstract

To study if MOSkin detectors coupled to a trans-rectal ultrasound (TRUS) probe may be used for in vivo dosimetry on the rectal wall surface during US-based HDR prostate brachytherapy and to quantify possible discrepancies between planned and delivered doses. MOSkins are a specific type of MOSFET dosimeter optimized to measure dose in steep dose gradients on interfaces. Two MOSkins were assembled on a TRUS probe used for on-line treatment planning. Measurements of the dose to the rectal wall were performed over 18 treatment sessions and compared to the doses calculated on the pre-treatment plan (DPRE) and reconstructed on post-treatment images (DPOST). Averages of the absolute differences between MOSkin readings and DPRE, MOSkin readings and DPOST and DPRE and DPOST were 6.7 ± 5.1%, 3.6 ± 1.9% and 6.3 ± 4.7%, respectively. Agreement between measurements and DPOST was significantly better than between measurements and DPRE (p=0.002) and DPRE and DPOST (p=0.004). Discrepancy between DPOST and DPRE correlated with the time required for treatment planning. MOSkin dosimeters integrated to the TRUS probe proved to be an accurate instrument for measuring the dose delivered to the rectal wall in HDR prostate brachytherapy. The delivered...Continue Reading

References

Nov 26, 1998·Medical Physics·G M DaskalovJ F Williamson
Nov 25, 2003·International Journal of Radiation Oncology, Biology, Physics·Bruce ThomadsenJudith Stitt
Apr 2, 2004·Strahlentherapie und Onkologie : Organ der Deutschen Röntgengesellschaft ... [et al]·Thomas MartinNikolaos Zamboglou
Aug 3, 2004·Physics in Medicine and Biology·Tsang CheungPeter K N Yu
Oct 19, 2006·Physics in Medicine and Biology·J LambertN Suchowerska
Apr 19, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Daniela WagnerRobert Michael Hermann
Oct 29, 2008·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Warren ToyeGillian Duchesne
Feb 25, 2009·Medical Physics·I S KwanV L Perevertaylo
Jun 24, 2010·Physics in Medicine and Biology·Nicholas HardcastleAnatoly B Rosenfeld
Nov 26, 2010·International Journal of Radiation Oncology, Biology, Physics·Natalka SuchowerskaDavid R McKenzie
Jun 29, 2011·Australasian Physical & Engineering Sciences in Medicine·Aisling HaugheyKoki Mugabe
Sep 21, 2011·Medical Physics·Erin L SeymourPeter Metcalfe
Sep 8, 2012·Journal of the National Comprehensive Cancer Network : JNCCN·James L MohlerDorothy A Shead
Jun 4, 2013·Clinical Oncology : a Journal of the Royal College of Radiologists·G C Morton, P J Hoskin
Jul 3, 2013·Applied Radiation and Isotopes : Including Data, Instrumentation and Methods for Use in Agriculture, Industry and Medicine·G GambariniA Rosenfeld
Jul 5, 2013·Medical Physics·Kari TanderupJoanna E Cygler
Dec 5, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Christian KirisitsFrank-André Siebert
Jul 10, 2014·The British Journal of Radiology·G KertzscherJ E Cygler
Aug 3, 2014·Brachytherapy·D Jeffrey Demanes, Michel I Ghilezan
Oct 18, 2014·Physics in Medicine and Biology·Z HanA B Rosenfeld

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Citations

Aug 25, 2016·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Kari TanderupRichard Pötter
Jun 20, 2017·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Ryan L SmithRick D Franich
Jul 1, 2020·Physics in Medicine and Biology·Anatoly B RozenfeldVladimir Feygelman
Oct 28, 2019·Australasian Physical & Engineering Sciences in Medicine·Z JamalludinN M Ung
Aug 18, 2020·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Joel PoderDean Cutajar
May 14, 2017·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·M CarraraA Rosenfeld

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