In vivo reflectance confocal microscopy of equivocal melanocytic lesions detected by digital dermoscopy follow-up

Journal of the European Academy of Dermatology and Venereology : JEADV
L LovattoSusana Puig

Abstract

Digital follow-up is a useful method for the detection of melanoma in atypical mole syndrome patients. The combination of digital follow-up (DFU) and reflectance confocal microscopy (RCM) could be useful to increase the accuracy in the classification of equivocal lesions in atypical mole syndrome patients. To assess the impact of RCM analysis on sensitivity and specificity of digital follow-up in a high-risk melanoma setting. Retrospective study with dermoscopy and RCM of consecutive equivocal atypical melanocytic lesions exhibiting changes in digital dermoscopy in a referral centre. Sixty-four lesions from 51 patients were included. Thirteen changing lesions (20.3%) corresponded to eight melanomas in situ and five invasive melanomas with Breslow less than 1 mm. Fifty-one lesions corresponded to melanocytic naevus with variable atypia. Total dermoscopy scores were not different between naevus and melanoma neither in the baseline (mean 5.06 and 5.24; P = 0.37) nor in the follow-up dermoscopic control (mean 5.44 and 5.55; P = 0.37). The only significant dermoscopic feature associated with melanoma in multivariate analysis was the presence of streaks after follow-up (P = 0.027; OR = 3.6; CI 1.50-8.70). The confocal microscopy eval...Continue Reading

References

Mar 21, 2002·The Lancet Oncology·H KittlerM Binder
Oct 11, 2002·Archives of Dermatology·Harald Kittler, Michael Binder
Jan 20, 2005·The British Journal of Dermatology·J BauerC Garbe
Mar 2, 2005·The Journal of Investigative Dermatology·Armin GergerJosef Smolle
Nov 29, 2005·Journal of the American Academy of Dermatology·Giovanni PellacaniStefania Seidenari
Sep 20, 2006·Archives of Dermatology·Harald KittlerScott Menzies
Jul 28, 2007·The Journal of Investigative Dermatology·Giovanni PellacaniScott Menzies
Oct 2, 2007·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Susana PuigJosep Malvehy
Jul 18, 2008·The Journal of Investigative Dermatology·Pascale GuiteraScott W Menzies
May 2, 2009·Journal of the American Academy of Dermatology·Sonia SeguraJosep Malvehy
Jun 11, 2011·Journal of the American Academy of Dermatology·Timo BuhlHolger A Haenssle
Nov 28, 2012·Journal of the European Academy of Dermatology and Venereology : JEADV·G SalerniH Kittler
Oct 11, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·B FerrariG Pellacani

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Citations

May 28, 2016·Journal of the European Academy of Dermatology and Venereology : JEADV·Y D XiongQ Chen
Jul 2, 2016·Dermatologic Clinics·Maria L MarinoAshfaq A Marghoob
Oct 4, 2016·Dermatologic Clinics·Cristina Carrera, Ashfaq A Marghoob
Oct 28, 2016·Lasers in Surgery and Medicine·Milind RajadhyakshaKishwer S Nehal
Jan 23, 2018·The British Journal of Dermatology·S BorsariC Longo
Oct 31, 2018·American Journal of Clinical Dermatology·Renato Marchiori BakosGabriel Salerni
Dec 7, 2018·The Cochrane Database of Systematic Reviews·Jacqueline DinnesUNKNOWN Cochrane Skin Cancer Diagnostic Test Accuracy Group
Sep 7, 2018·The American Journal of Dermatopathology·Andrew KelseyAlon Scope
Jan 31, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·C PezziniG Pellacani
Sep 24, 2019·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Xiaofang ZengWenzhong Xiang
Jun 5, 2020·International Journal of Dermatology·Anna Pogorzelska-AntkowiakPaola Corneli
May 28, 2016·Biomedical Optics Express·Yael BishitzZeev Zalevsky
Dec 7, 2018·The Cochrane Database of Systematic Reviews·Jacqueline DinnesUNKNOWN Cochrane Skin Cancer Diagnostic Test Accuracy Group
Sep 8, 2018·Melanoma Management·Andréanne WaddellPascale Guitera
Oct 18, 2020·Lasers in Medical Science·Catherine ReillyBabar K Rao
Nov 10, 2020·International Journal of Dermatology·Anna Pogorzelska-Antkowiak, Jacek Calik
May 27, 2020·Journal of the American Academy of Dermatology·Cristian Navarrete-DechentManu Jain
Jun 20, 2020·Journal of the American Academy of Dermatology·Neda ShahriariAlon Scope
Mar 23, 2021·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Anna Pogorzelska-AntkowiakMarina Agozzino
Apr 7, 2021·Journal of the American Academy of Dermatology·Alessandra Grazia CondorelliGiovanni Pellacani
Nov 2, 2021·Journal of Cosmetic Dermatology·Yashdeep Singh PathaniaMohamad Goldust
Jul 30, 2020·Anti-cancer Agents in Medicinal Chemistry·Suresh MadheswaranStefan Barth

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