PMID: 6171065Aug 1, 1981Paper

In vivo regulation of ovarian activity by alpha-fetoprotein

Steroids
C AusselC Stora

Abstract

Adult female rats, each injected with 760 microgram alpha-fetoprotein (AFP) weekly, presented after the third week a decrease of ovarian activity evidenced by a decreased number of maturing follicles, corpora lutea, and a drop in ovarian weight. The level of progesterone was low and agreed with the decreased number of corpora lutea. Conversely, total and free estradiol-17 beta levels remained normal despite the known ability of AFP to bind estrogenic hormones. A regulatory role of AFP during the postnatal stage of sexual maturation is proposed.

References

Sep 1, 1975·Journal of Immunological Methods·R Maiolini, R Masseyeff
Sep 1, 1976·Steroids·G ValletteM F Jayle
Dec 1, 1976·Proceedings of the National Academy of Sciences of the United States of America·E Ruoslahti, E Engvall
May 19, 1977·Nature·R A MurgitaH Wigzell
May 1, 1978·Journal of Reproduction and Fertility·T B PoolI L Cameron
Jun 1, 1978·Journal of Steroid Biochemistry·C Aussel, R Masseyeff
Sep 1, 1979·Journal of the National Cancer Institute·C Sonnenscheln, A M Soto
Jan 1, 1971·Advances in Cancer Research·G I Abelev
Jul 31, 1980·Biochemical and Biophysical Research Communications·C AusselB Krebs
Feb 1, 1980·Journal of the National Cancer Institute·C Sonnenschein, A M Soto

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Citations

Jan 1, 1986·Prostaglandins, Leukotrienes, and Medicine·C Aussel, R Negrel
Jul 12, 1983·Biochimica Et Biophysica Acta·C Aussel, R Masseyeff
Oct 15, 1982·Biochemical and Biophysical Research Communications·C Aussel, D Castelli
Aug 30, 1983·Biochemical and Biophysical Research Communications·C Aussel, R Masseyeff
Apr 8, 2014·Cancer Prevention Research·Herbert I JacobsonJames A Bennett

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