In vivo sites and cellular mechanisms of T reg cell-mediated suppression

The Journal of Experimental Medicine
Alexander Y Rudensky, Daniel J Campbell

Abstract

Regulatory CD4 T (T reg) cells control immune responses to self-antigens and pathogens. However, where T reg cells act to curtail effector T cells in vivo and what stage of effector T cell activation or differentiation is targeted by T reg cells remain unknown. Furthermore, a requirement for direct effector T cell-T reg cell contact in vivo has not been ascertained. Varying answers to these important questions have been provided by several new studies.

References

Nov 28, 2001·Immunological Reviews·E M ShevachA M Thornton
Sep 2, 2003·Proceedings of the National Academy of Sciences of the United States of America·E Allison GreenRichard A Flavell
Jul 6, 2004·Proceedings of the National Academy of Sciences of the United States of America·Silke PaustHarvey Cantor
Aug 17, 2004·Immunity·Chyi-Song HsiehAlexander Y Rudensky
Oct 7, 2004·European Journal of Immunology·Qizhi TangJeffrey A Bluestone
Dec 30, 2004·Proceedings of the National Academy of Sciences of the United States of America·Mei-Ling ChenKhashayarsha Khazaie
Feb 9, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·David C GondekRandolph J Noelle
Mar 9, 2005·The Journal of Experimental Medicine·Linda FahlénFiona Powrie
Mar 16, 2005·Current Opinion in Immunology·Cristina Cozzo Picca, Andrew J Caton
Mar 24, 2005·Nature Immunology·Harald von Boehmer
Apr 23, 2005·The Journal of Immunology : Official Journal of the American Association of Immunologists·Isabelle SuffiaYasmine Belkaid
Oct 19, 2005·The Journal of Experimental Medicine·François GhiringhelliLaurence Zitvogel
Nov 23, 2005·The Journal of Experimental Medicine·Zhibin ChenChristophe Benoist
Nov 29, 2005·Nature Immunology·Qizhi TangJeffrey A Bluestone
Mar 15, 2006·Nature Immunology·Chyi-Song HsiehAlexander Y Rudensky
Mar 15, 2006·The Journal of Experimental Medicine·Carlos E TadokoroMichael L Dustin
Mar 15, 2006·The Journal of Experimental Medicine·Isabelle J SuffiaYasmine Belkaid

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Citations

Mar 31, 2010·Cancer Immunology, Immunotherapy : CII·Yuqiang Ji, Wanggang Zhang
Sep 18, 2010·Cancer Immunology, Immunotherapy : CII·Max WarnckeHendrik Veelken
Dec 1, 2010·Immunologic Research·Ana M Sanchez, Yiping Yang
Nov 30, 2011·Immunology and Cell Biology·Hongtao ZhangMark I Greene
Dec 8, 2007·Nature Reviews. Immunology·Andrew L Mellor, David H Munn
May 9, 2009·Proceedings of the National Academy of Sciences of the United States of America·Jason M WeaverAndrea J Sant
Aug 5, 2008·Viral Immunology·Velislava Terzieva
Feb 22, 2008·Journal of Gastroenterology and Hepatology·Ian R van Driel, Desmond K Y Ang
Feb 20, 2010·Mediators of Inflammation·Franco PandolfiGiovanni Cammarota
Mar 16, 2007·Proceedings of the National Academy of Sciences of the United States of America·Zacarias GarciaPhilippe Bousso
Dec 17, 2009·Cytokine & Growth Factor Reviews·Brian RuffellLisa M Coussens
Jan 2, 2008·Clinical Immunology : the Official Journal of the Clinical Immunology Society·Valeria ToselloMaha Ayyoub
Mar 4, 2008·British Journal of Pharmacology·M SitkovskyA Ohta
Jan 15, 2015·Immunology and Cell Biology·Zachary ChowMichael J Hickey
Jun 9, 2016·Journal of Neuroinflammation·Giacomo CasellaRoberto Furlan
Jul 29, 2016·Scientific Reports·Young-Sun LeeHyon-Seung Yi
Jun 24, 2009·Transplantation Proceedings·M KarczewskiM Glyda
Jan 20, 2015·American Journal of Reproductive Immunology : AJRI·Monika FijakAndreas Meinhardt
Jul 13, 2007·Immunological Reviews·Adam MorMark R Philips
Jul 10, 2007·The Journal of Immunology : Official Journal of the American Association of Immunologists·Richard A O'ConnorStephen M Anderton
Apr 28, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Chiara CamisaschiChiara Castelli
Apr 28, 2012·The Journal of Immunology : Official Journal of the American Association of Immunologists·Aki UedaPaul L Stein
Jul 24, 2012·Advanced Materials·Siddharth JhunjhunwalaSteven R Little
Mar 7, 2008·The Journal of Immunology : Official Journal of the American Association of Immunologists·Annie W T LauJohn V Forrester
Dec 18, 2010·Expert Review of Clinical Immunology·Pawel MrozMichael R Hamblin

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