PMID: 9160943May 1, 1997Paper

In vivo skeletal responses to porous-surfaced implants subjected to small induced motions

The Journal of Bone and Joint Surgery. American Volume
M JastyW H Harris

Abstract

Cylindrical porous-coated implants were placed in the distal femoral metaphyses of twenty dogs and were subjected to zero, twenty, forty, or 150 micrometers of oscillatory motion for eight hours each day for six weeks with use of a specially designed loading apparatus. The in vivo skeletal responses to the different magnitudes of relative motion were evaluated. Histological analysis demonstrated growth of bone into the porous coatings of all of the implants, including those that had been subjected to 150 micrometers of motion. However, the ingrown bone was in continuity with the surrounding bone only in the groups of implants that had not been subjected to motion or that had been subjected to twenty micrometers of motion; in contrast, the implants that had been subjected to forty micrometers of motion were surrounded in part by trabecular bone but also in part by fibrocartilage and fibrous tissue, and those that had been subjected to 150 micrometers of motion were surrounded by dense fibrous tissue. Trabecular microfractures were identified around three of the five implants that had been subjected to forty micrometers of motion and around four of the five that had been subjected to 150 micrometers of motion, suggesting that the...Continue Reading

Citations

Mar 2, 2005·Clinical Orthopaedics and Related Research·Søren KoldKjeld Søballe
Apr 28, 2007·The Journal of Bone and Joint Surgery. British Volume·I UdofiaP Grigoris
Jan 11, 2008·Journal of Biomedical Materials Research. Part a·Henrik DaugaardKjeld Soballe
Mar 4, 2011·The Journal of Bone and Joint Surgery. American Volume·Harpal S KhanujaMichael A Mont
Apr 28, 2011·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D P Pioletti
Nov 1, 2011·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Bidyut Pal, Sanjay Gupta
Apr 18, 2012·Acta Orthopaedica. Supplementum·Tina Strømdal Wik
Mar 22, 2013·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Rajesh GhoshMartin Browne
Mar 26, 2014·Clinical Orthopaedics and Related Research·Arun KannanWilliam A Jiranek
Mar 27, 2015·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Florian SchmidutzVolker Braunstein
Aug 1, 2016·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Kaushik Mukherjee, Sanjay Gupta
Apr 12, 2016·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Niklas B DammNicholas E Bishop
Feb 7, 2017·Hip International : the Journal of Clinical and Experimental Research on Hip Pathology and Therapy·Ahmed Nageeb MahmoudGunnar Flivik
Jan 13, 2017·Journal of Orthopaedics and Traumatology : Official Journal of the Italian Society of Orthopaedics and Traumatology·Nathan T FormainiCooper Wilson
Oct 13, 2017·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Richard J van ArkelJonathan R T Jeffers
Jun 6, 2019·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Spencer C BarnesJonathan R T Jeffers
Nov 7, 2019·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Miguel A DiazMark A Frankle
Aug 27, 2019·Shoulder & Elbow·Tanujan ThangarajahSimon Lambert
Nov 28, 2019·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Souptick ChandaDilip Kumar Pratihar
Feb 23, 2020·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Dermot O'Rourke, Mark Taylor
Feb 14, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Edward C A GeeAdnan Saithna
Dec 4, 2002·Clinical Orthopaedics and Related Research·S A HackingJ D Bobyn
Dec 28, 1999·Clinical Orthopaedics and Related Research·W J MaloneyS T Woolson
Oct 18, 2002·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Nozomu InoueEdmund Y S Chao
Mar 27, 2001·Computer Methods in Biomechanics and Biomedical Engineering·A. Hashemi, A. Shirazi-Adl
Jun 6, 2006·Acta Orthopaedica·Mikael SundfeldtChristina Gretzer
Feb 8, 2006·Journal of Spinal Disorders & Techniques·Robin HitchcockWilliam R Walsh
Apr 2, 2004·Clinical Orthopaedics and Related Research·Michael R O'RourkeAaron G Rosenberg
Aug 15, 2006·Clinical Orthopaedics and Related Research·Michael D RiesMartin Anderson
Nov 15, 2005·Spine·Wade K JensenJeffrey P Rouleau
Mar 17, 2010·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·D JanssenN Verdonschot
Sep 2, 2011·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Dennis JanssenNico Verdonschot
Feb 4, 2012·Computer Methods in Biomechanics and Biomedical Engineering·M A Pérez, B Seral-García
Jan 4, 2012·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Bas van der PloegNico Verdonschot
Sep 20, 2011·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·T S WikA Aamodt
Apr 13, 2011·Clinical Orthopaedics and Related Research·Matthew WalkerMark Frankle
Mar 25, 2015·BioMed Research International·Antonio HerreraLuis Gracia
Oct 10, 2015·Veterinary and Comparative Orthopaedics and Traumatology : V.C.O.T·H M KoraniS C Roe
Sep 1, 2015·European Journal of Orthopaedic Surgery & Traumatology : Orthopédie Traumatologie·Nobuhiro KakuHiroshi Tsumura
Aug 18, 2016·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Patrick J DenardAnthony A Romeo
May 18, 2018·Journal of Orthopaedic Surgery and Research·Koji TotoribeGang Deng
Jan 11, 2018·Journal of Biomaterials Science. Polymer Edition·Handong XuXuehui Yang

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.