In vivo study of an antimicrobial surgical drape system.

Journal of Clinical Microbiology
J ConnC M Herring

Abstract

We performed a double-blind clinical study to determine the efficacy of nonwoven laparotomy drapes in which 3-(trimethoxysilyl)propyldimethyloctadecyl ammonium chloride, an antimicrobial agent, was chemically bonded to the absorbent reinforcement surrounding the fenestration. The reinforcement portion of the surgical drape that contained the fenestration was segmented into four identical-appearing sections, two on each side of the fenestration. One segment on each side was antimicrobial. The locations of the treated segments were randomly varied. At the end of each operation, test strips were removed. Bacteria were harvested from each segment by mechanical agitation. Bacterial CFU were counted. There were 110 surgical cases in the study, including clean, clean contaminated, and contaminated procedures. Data analysis divided the cases into two distinct groups. Group 1 was composed of 59 cases in which less than 30 total CFU was recovered from the four test samples. The average duration of surgery for this group was 1.8 h. Group 2 was composed of 51 cases in which bacterial recovery was in excess of 30 CFU per procedure (range, 30 to 25,000 bacterial CFU). The average duration of surgery was 3.3 h. Bacterial reduction in the trea...Continue Reading

References

Nov 1, 1978·Applied and Environmental Microbiology·A J Isquith, C J McCollum
Jul 1, 1978·The British Journal of Surgery·W WhyteJ Graham
Jan 25, 1969·Lancet·J Charnley, N Eftekhar
May 1, 1973·American Journal of Surgery·D J AlfordJ B Hart
May 1, 1971·The British Journal of Surgery·A E DavidsonG Smith
Jan 1, 1957·The Journal of Infectious Diseases·D SOMPOLINSKYJ E RIPPON

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Citations

Sep 1, 1988·Journal of Clinical Microbiology·P R MurrayR L Heeren

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