PMID: 9171396Jun 1, 1997Paper

In vivo supercoiling of plasmid and chromosomal DNA in an Escherichia coli hns mutant

Journal of Bacteriology
F J Mojica, C F Higgins

Abstract

We have used trimethylpsoralen to measure localized levels of unconstrained DNA supercoiling in vivo. The data provide direct evidence that plasmid and chromosomal DNA supercoiling is altered in vivo in an hns mutant. This increase in supercoiling is independent of transcription or changes in the activity of topoisomerase I. These data have implications for the mechanisms by which the chromatin-associated protein H-NS may influence chromosome organization and gene expression.

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Citations

Jan 13, 2006·Molecular Genetics and Genomics : MGG·M HildebrandK Geider
Aug 28, 2010·Proceedings of the National Academy of Sciences of the United States of America·Stefan T AroldJohn E Ladbury
Jul 19, 2011·Journal of Bacteriology·Sabrina S AliWilliam Wiley Navarre
Nov 21, 2001·The Journal of Biological Chemistry·Remus Thei DameNora Goosen
Jun 8, 2007·Nucleic Acids Research·Nicole A BeckerL James Maher
Jul 26, 2016·Frontiers in Molecular Biosciences·Leise RiberAnders Løbner-Olesen
Sep 12, 2002·Biological Chemistry·Oliver Schröder, Rolf Wagner
Nov 30, 2011·Proceedings of the National Academy of Sciences of the United States of America·Fenfei LengDavid D Dunlap
Apr 28, 2005·Molecular Microbiology·Richard A SteinN Patrick Higgins
Apr 2, 2013·DNA Research : an International Journal for Rapid Publication of Reports on Genes and Genomes·Takeshi UedaTaku Oshima
May 29, 2016·The FEBS Journal·Francisco J M Mojica, Francisco Rodriguez-Valera
Oct 22, 1998·Molecular Microbiology·P Staczek, N P Higgins
Oct 10, 2001·Journal of Bacteriology·M M Barker, R L Gourse
Sep 28, 1998·Journal of Bacteriology·S PalchaudhuriM A Leon
Feb 6, 2007·International Journal of Medical Microbiology : IJMM·Fang YeSebastian Suerbaum
Sep 25, 1999·Journal of Molecular Biology·A M AbrilJ M Hermoso
Apr 4, 2000·Current Opinion in Microbiology·M Yarmolinsky
Aug 1, 2009·EcoSal Plus·Akira Ishihama
Jun 25, 2015·Microbiology Spectrum·N Patrick Higgins, Alexander V Vologodskii
Aug 6, 2003·Journal of Molecular Biology·Claudio O GualerziCynthia L Pon

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