In vivo trabecular bone morphologic and mechanical relationship using high-resolution 3-T MRI

AJR. American Journal of Roentgenology
Angel Alberich-BayarriDavid Moratal

Abstract

The purpose of this study was to investigate the in vivo morphologic and elastic parameters of trabecular bone with high-resolution 3-T MRI in a healthy reference population. A series of wrist MR images were acquired with high-spatial-resolution (180 mum) isotropic voxels from 40 subjects without reported bone disease. After image postprocessing, the bone volume-to-total volume ratio, trabecular thickness, trabecular separation, and trabecular number were calculated in the morphologic analysis. Trabecular bone was mechanically simulated using the finite-element method to calculate the apparent elastic modulus parameter. The relationship between morphologic and mechanical parameters was studied. The influence of the analyzed bone volume was also investigated. Statistically significant sex influences were found on the bone volume-to-total volume ratio (p = 0.003), trabecular thickness (p = 0.02), and apparent elastic modulus (p = 0.01); these parameters were lower in women. However, trends were found only on trabecular separation (p = 0.06) and trabecular number (p = 0.07). Age had no statistically significant influence in any morphologic (bone volume-to-total volume ratio, r = -0.24, p = 0.13; trabecular thickness, r = -0.03, p ...Continue Reading

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Citations

Dec 25, 2012·Calcified Tissue International·Subburaman MohanBouchra Edderkaoui
Aug 29, 2013·Tissue Engineering. Part a·Po-Chun ChangChi-Hwa Wang
May 26, 2012·TheScientificWorldJournal·Tomasz TopolińskiKrzysztof Nowicki
Jul 8, 2011·Radiología·L Martí BonmatíJ V Manjón Herrera
Dec 27, 2012·IEEE Transactions on Bio-medical Engineering·Waldir L RoqueAngel Alberich-Bayarri
Dec 14, 2011·Journal of Ethnopharmacology·Yu-Jen KoWen-Chuan Lin
Feb 25, 2020·Journal of the Mechanical Behavior of Biomedical Materials·Emily L ArnoldCharlene Greenwood
May 2, 2021·Clinical and Translational Medicine·Sowmya RameshVrisha Madhuri

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