In Vivo Validation of a 3-D Ultrasound System for Imaging the Lateral Ventricles of Neonates

Ultrasound in Medicine & Biology
Jessica KishimotoSandrine de Ribaupierre

Abstract

Intra-ventricular hemorrhage, with the resultant cerebral ventricle dilation, is a common cause of brain injury in preterm neonates. Clinically, monitoring is performed using 2-D ultrasound (US); however, its clinical utility in dilation is limited because it cannot provide accurate measurements of irregular volumes such as those of the ventricles, and this might delay treatment until the patient's condition deteriorates severely. We have developed a 3-D US system to image the lateral ventricles of neonates within the confines of incubators. We describe an in vivo ventricle volume validation study in two parts: (i) comparisons between ventricle volumes derived from 3-D US and magnetic resonance images obtained within 24 h; and (ii) the difference between 3-D US ventricle volumes before and after clinically necessary interventions (ventricle taps), which remove cerebral spinal fluid. Magnetic resonance imaging ventricle volumes were found to be 13% greater than 3-D US ventricle volumes; however, we observed high correlations (R(2) = 0.99) when comparing the two modalities. Differences in ventricle volume pre- and post-intervention compared with the reported volume of cerebrospinal fluid removed also were highly correlated (R(2) ...Continue Reading

References

Jun 1, 2001·Physics in Medicine and Biology·A FensterH N Cardinal
Aug 31, 2001·Ultrasound in Medicine & Biology·J H GilmoreM A Kliewer
Jul 2, 2002·Archives of Disease in Childhood. Fetal and Neonatal Edition·B P MurphyJ J Volpe
Aug 21, 2003·European Radiology·M RiccabonaD P Pretorius
Jan 18, 2005·Ultrasound in Medicine & Biology·Nadja HaidenChristina Kohlhauser-Vollmuth
Feb 3, 2009·Cerebrospinal Fluid Research·David ShoomanOwen Sparrow
Jan 20, 2010·Pediatric Nephrology : Journal of the International Pediatric Nephrology Association·Alison L KentMichael C Falk
Feb 4, 2011·Archives of Disease in Childhood. Fetal and Neonatal Edition·Andrew Whitelaw, Kristian Aquilina
Sep 20, 2011·Early Human Development·Sylke J SteggerdaGerda van Wezel-Meijler

❮ Previous
Next ❯

Citations

Dec 16, 2017·Journal of Paediatrics and Child Health·Glenda McLeanSuzanne L Miller
Aug 31, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Marcus LoSandrine de Ribaupierre
Dec 30, 2020·American Journal of Perinatology·Priyanka RoySandrine de Ribaupierre

❮ Previous
Next ❯

Related Concepts

Related Feeds

Brain Injury & Trauma

brain injury after impact to the head is due to both immediate mechanical effects and delayed responses of neural tissues.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.