In vivo validation of the in silico predicted pressure drop across an arteriovenous fistula

Annals of Biomedical Engineering
Leonard D BrowneM T Walsh

Abstract

The creation of an arteriovenous fistula offers a unique example of vascular remodelling and adaption. Yet, the specific factors which elicit remodelling events which determine successful maturation or failure have not been unambiguously determined. Computational fluid dynamic (CFD) simulations are increasingly been employed to investigate the interaction between local hemodynamics and remodelling and can potentially be used to assist in clinical risk assessment of maturation or failure. However, these simulations are inextricably linked to their prescribed boundary conditions and are reliant on in vivo measurements of flow and pressure to ensure their validity. The study compares in vivo measurements of the pressure distribution across arteriovenous fistulae against a representative numerical model. The results of the study indicate relative agreement (error ≈ 8-10%) between the in vivo and CFD prediction of the mean pressure drop across the AVFs. The large pressure drop across the AVFs coincided with a palpable thrill (perivascular vibration) in vivo and fluctuations were observed in the numerical pressure drop signal due to flow instabilities arising at the anastomosis. This study provides a benchmark of the pressure distrib...Continue Reading

References

May 22, 2002·Journal of the American College of Cardiology·James A ShawAnthony M Dart
May 29, 2002·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Jean-Marc CorpatauxDaniel Hayoz
Jan 25, 2003·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Jan H M TordoirTik Ien Yo
May 21, 2005·Asian Cardiovascular & Thoracic Annals·A Kubilay KorkutErtan Onursal
Jul 19, 2005·Journal of Biomechanics·Rebecca J GusicKeith J Gooch
May 30, 2006·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Joke van der LindenMarinus A van den Dorpel
May 4, 2007·Journal of the American Society of Nephrology : JASN·Timmy LeeMichael Allon
Aug 21, 2007·Clinical Journal of the American Society of Nephrology : CJASN·Arif AsifGerald A Beathard
Nov 27, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Yang WangPrabir Roy-Chaudhury
May 30, 2008·Journal of the American Society of Nephrology : JASN·Anatole Besarab
May 26, 2009·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·E KortenR P Tutein Nolthenius
Sep 17, 2009·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Mufaddal F KhedaWilliam D Paulson
Mar 29, 2012·Seminars in Dialysis·Timmy LeePrabir Roy-Chaudhury
Aug 16, 2012·Seminars in Dialysis·Ehsan Rajabi-JagahrghRupak K Banerjee
Nov 29, 2012·Annals of Biomedical Engineering·Monica SigovanDavid Saloner
Jan 3, 2013·Seminars in Dialysis·Ehsan Rajabi-JagahrghRupak K Banerjee
Feb 1, 2013·Journal of Biomechanical Engineering·Patrick M McGahAlberto Aliseda
Sep 17, 2013·Biomechanics and Modeling in Mechanobiology·Patrick M McGahAlberto Aliseda
Dec 18, 2013·Journal of Vascular Surgery·Yong HeScott A Berceli
Feb 5, 2014·International Journal for Numerical Methods in Biomedical Engineering·Iolanda DecoratoAnne-Virginie Salsac

❮ Previous
Next ❯

Citations

Aug 3, 2018·International Journal for Numerical Methods in Biomedical Engineering·Nicolas AristokleousMichael T Walsh
Apr 11, 2019·Journal of Biomechanical Engineering·Simone StellaGiorgio Prouse
Mar 28, 2017·Biomechanics and Modeling in Mechanobiology·R AgujetasJ M Montanero
Jul 29, 2017·Cardiovascular Engineering and Technology·Andrea Remuzzi, Michela Bozzetto
Nov 19, 2015·Cardiovascular Engineering and Technology·Leonard D BrownePhilip Griffin
Jul 28, 2017·Cardiovascular Engineering and Technology·L GrechyP E Vincent
Jul 1, 2017·Cardiovascular Engineering and Technology·Bogdan Ene-Iordache, Andrea Remuzzi
Jul 27, 2017·Cardiovascular Engineering and Technology·Marco Franzoni, Michael T Walsh
Jul 1, 2020·Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine·Eamonn ColleyTracie Barber
Dec 21, 2021·Frontiers in Bioengineering and Biotechnology·Hannah NorthrupYan-Ting Shiu

❮ Previous
Next ❯

Related Concepts

Related Feeds

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.