In wealthier countries, patients perceive worse impact of the disease although they have lower objectively assessed disease activity: results from the cross-sectional COMORA study

Annals of the Rheumatic Diseases
Polina PutrikAnnelies Boonen

Abstract

To investigate patterns in patient-reported and physician-reported disease outcomes in patients with rheumatoid arthritis (RA) from countries with different level of socioeconomic development. Data from a cross-sectional multinational study (COMOrbidities in RA) were used. Contribution of socioeconomic welfare (gross domestic product (GDP); low vs high) of country of residence to physician-reported (tender joint count, swollen joint count (SJC), erythrocyte sedimentation rate, disease activity score based on 28 joints assessment (DAS28)-3v based on these three components and physician global assessment) and patient-reported (modified Health Assessment Questionnaire (mHAQ), patient global assessment and fatigue) disease outcomes was explored in linear regressions, adjusting for relevant confounders. In total, 3920 patients with RA from 17 countries (30 to 411 patients per country) were included, with mean age of 56 years (SD13) and 82% women. Mean SJC varied between 6.7 (Morocco) and 0.9 (The Netherlands), mean mHAQ ranged between 0.7 (Taiwan) and 1.5 (The Netherlands). Venezuela had the lowest (1.7) and the Netherlands the highest score on fatigue (5.0). In fully adjusted models, lower GDP was associated with worse physician-re...Continue Reading

References

Feb 1, 1991·Pain·H P Greenwald
Oct 10, 1998·Cancer Practice·G JuarezT Borneman
Dec 10, 2003·Pain Management Nursing : Official Journal of the American Society of Pain Management Nurses·Lynn Clark CallisterKatri Vehvilainen-Julkunen
Aug 13, 2005·European Journal of Pain : EJP·Harald BreivikDerek Gallacher
Oct 7, 2005·Arthritis and Rheumatism·Sarah HewlettMaggie Hehir
Nov 30, 2011·Clinical Rheumatology·Richard Charles John CampbellDavid L Scott
Sep 5, 2014·Arthritis Care & Research·Bryant R EnglandKaleb Michaud

❮ Previous
Next ❯

Citations

Mar 11, 2016·Annals of the Rheumatic Diseases·Thomas DörnerGerd R Burmester
Mar 24, 2017·PloS One·Cynthia S CrowsonUNKNOWN A Trans-Atlantic Cardiovascular Risk Consortium for Rheumatoid Arthritis (ATACC-RA)
Apr 8, 2017·Current Rheumatology Reports·Patricia Katz
Sep 2, 2017·Rheumatology·Ricardo J O FerreiraUNKNOWN CoimbRA investigators, RAID investigators and COMEDRA investigators
Apr 24, 2018·Expert Review of Clinical Immunology·Tania Gudu, Laure Gossec
Apr 11, 2017·Current Medicinal Chemistry·Laszlo GulacsiPeter L Lakatos
Aug 22, 2018·Annals of the Rheumatic Diseases·Ricardo J O FerreiraJose A P da Silva
Jun 27, 2019·Rheumatology·Elena NikiphorouBrandon A Kohrt
May 16, 2017·The British Journal of Dermatology·L Puig, P Putrik
Jul 13, 2016·Current Rheumatology Reports·Filipe C AraújoJoão Eurico Fonseca
Sep 14, 2020·Joint, Bone, Spine : Revue Du Rhumatisme·Catia DuarteJosé António Pereira da Silva

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.