PMID: 8969357Dec 1, 1996Paper

Inability to attain oral anticoagulation: warfarin-rifampin interaction revisited

Southern Medical Journal
P R Casner

Abstract

The warfarin-rifampin interaction is a well-described but underappreciated drug interaction. A case is reported in which therapeutic anticoagulation could not be achieved after nearly 4 weeks of warfarin therapy because of simultaneous administration of rifampin. This patient had the highest warfarin clearance ever reported in the literature. The world's literature describing warfarin-rifampin interactions for the past 32 years was reviewed to suggest guidelines for warfarin dosage when rifampin is given simultaneously.

Citations

May 7, 2013·BMC Pharmacology & Toxicology·Maria A P MartinsAntônio L P Ribeiro
Jun 2, 2007·Progress in Cardiovascular Nursing·Karissa Y KimHattie Alexandropoulos
Apr 11, 2020·Clinical Pharmacology and Therapeutics·Meijia ZhouSean Hennessy
Oct 19, 2017·The Journal of Pediatric Pharmacology and Therapeutics : JPPT : the Official Journal of PPAG·Michael PoonDonald L Yee
Jan 8, 2021·European Journal of Clinical Pharmacology·Charlotte S YangTammy J Bungard
Feb 6, 2021·Pharmacogenomics and Personalized Medicine·Muhammad SalemHazem Elewa
Mar 2, 2021·World Journal of Clinical Cases·Ya-Ni HuShu-Sen Sun

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