PMID: 8445178Jan 1, 1993Paper

Inability to validate a predictive score for infective endocarditis in intravenous drug users

The Journal of Emergency Medicine
G P YoungJ Reeves

Abstract

We sought to identify presenting features that should increase the accuracy of diagnosis of endocarditis in symptomatic intravenous drug use (IVDU) patients. We used two data sets of IVDU patients to develop and validate a score for endocarditis. A retrospective analysis of admitted IVDU patients was conducted with subsequent validation of endocarditis score on consecutive admitted IVDU patients at the same urban teaching hospital emergency department. Statistical comparison was made of presenting clinical features in patients with and without positive blood cultures or vegetation on their echocardiogram. Multivariable analysis of significant features was carried out. A clinical score was developed using a likelihood ratio to determine weighting. Validation of the score was tested by application to a second set of admitted symptomatic IVDU patients. The performance of the score was assessed by comparison of receiver operating characteristic curves for the two data sets. Factors associated with endocarditis on multivariable analysis were past history of endocarditis (negative correlation), total white blood cell (WBC) count, percentage neutrophils and bands on differential WBC count, infiltrate on chest x-ray, and arterial oxyge...Continue Reading

References

Jan 1, 1979·The American Journal of Medicine·E L Pesanti, I M Smith
Apr 1, 1991·Annals of Emergency Medicine·K A Delaney
May 1, 1990·Journal of General Internal Medicine·M D Stein
Jul 1, 1990·The American Journal of Medicine·J H SametD E Singer
Jan 27, 1989·JAMA : the Journal of the American Medical Association·R E ChaissonA R Moss
Jun 1, 1987·Annals of Internal Medicine·E G Wilkins
Mar 1, 1988·Postgraduate Medicine·P R Haller
Mar 1, 1986·Annals of Emergency Medicine·G P Young
May 1, 1986·Archives of Internal Medicine·L Weinstein
Feb 1, 1987·Annals of Internal Medicine·M D Aronson, D H Bor
Mar 1, 1987·British Heart Journal·I R Gray
Apr 1, 1987·Medical Decision Making : an International Journal of the Society for Medical Decision Making·R J PanzerP F Griner
Jun 1, 1987·Annals of Internal Medicine·P R MarantzG H Friedland
Nov 1, 1987·Stroke; a Journal of Cerebral Circulation·R G HartS E Joerns
Dec 1, 1987·Archives of Internal Medicine·M E CharlsonC R MacKenzie
Sep 1, 1986·Journal of General Internal Medicine·T G Tape, R J Panzer
Mar 1, 1987·The American Journal of Emergency Medicine·D P Sklar, R Rusnak
Sep 26, 1985·The New England Journal of Medicine·J H WassonL Goldman
Feb 1, 1986·The American Journal of Medicine·M J RobbinsJ A Strom
Mar 1, 1984·The New England Journal of Medicine·R M CentorJ P Wood
Oct 1, 1981·The New England Journal of Medicine·M A FischlL B Gardner

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Citations

Dec 17, 2002·Journal of Neurotrauma·Yasutsugu YukawaLawrence G Lenke
Jun 15, 2011·Journal of Neurotrauma·Shyam Aravamudhan, Ravi V Bellamkonda
Dec 2, 1998·Journal of Neurosurgery·E EmeryA D Levi
Oct 10, 2002·Infectious Disease Clinics of North America·Patricia D Brown, Donald P Levine
Jun 25, 2015·Journal of General Internal Medicine·Yingda XieAlan J Hunter
Feb 25, 2014·The American Journal of Emergency Medicine·Hangyul Chung-EsakiBitou Cisse
Aug 24, 1999·Journal of Child Neurology·M R PrasadJ Baumgartner

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