Inactivation of aflatoxin B1 by using the synergistic effect of hydrogen peroxide and gamma radiation.

Applied and Environmental Microbiology
U D PatelP J Dave

Abstract

Inactivation of aflatoxin B1 was studied by using gamma radiation and hydrogen peroxide. A 100-krad dose of gamma radiation was sufficient to inactivate 50 micrograms of aflatoxin B1 in the presence of 5% hydrogen peroxide, and 400 krad was required for total degradation of 100 micrograms of aflatoxin in the same system. Degradation of aflatoxin B1 was confirmed by high-pressure liquid chromatographic and thin-layer chromatographic analysis. Ames microsomal mutagenicity test showed loss of aflatoxin activity. This method of detoxification also reduces the toxin levels effectively in artificially contaminated groundnuts.

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Feb 3, 1999·Annals of the New York Academy of Sciences·D L LiuW Q Chen
Sep 17, 2004·Food Additives and Contaminants·A D ProctorI Goktepe
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Jan 15, 2021·Comprehensive Reviews in Food Science and Food Safety·Sara Schaarschmidt, Carsten Fauhl-Hassek

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