Inadequate Minority Representation within SARS-CoV-2 Vaccine Trials

The American Journal of Tropical Medicine and Hygiene
Joshua F CraftJohn J Openshaw

Abstract

Minority communities have borne the brunt of COVID-19 disease in the United States. Nonwhites have contracted most of the SARS-CoV-2 infections; COVID-19 mortality rates for Black Americans are more than twice those for whites. Given this, studying the most effective ways to prevent and treat SARS-CoV-2 in these populations should be a research priority, particularly with respect to vaccine trials. Federal guidelines from the National Institutes of Health and Food and Drug Administration emphasize the need for inclusion of minority groups in these trials, but none of the publicly available SARS-CoV-2 vaccine trial protocols requires representative sampling of minorities. This piece emphasizes the importance of adequate inclusion of minority communities in SARS-CoV-2 vaccine trials, and the implications of this inclusion for SARS-CoV-2 vaccine distribution.

References

Oct 1, 1955·American Journal of Public Health and the Nation's Health·O L ANDERSON
Jun 20, 2020·MMWR. Morbidity and Mortality Weekly Report·Erin K StokesKathleen E Fullerton
Aug 14, 2020·JAMA : the Journal of the American Medical Association·Mary Chris Jaklevic

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