Inadequate sleep as a contributor to impaired glucose tolerance: A cross-sectional study in children, adolescents, and young adults with circadian rhythm sleep-wake disorder.

Pediatric Diabetes
Makiko ToyouraYukuo Konishi

Abstract

Sleep deprivation and circadian disruption are associated with decreased insulin sensitivity and hyperglycemia. It is uncertain whether circadian sleep-wake disorder (CRSWD), which relates to both the homeostatic sleep system and the circadian timing system, affects glycemic regulation and insulin secretion. We aimed to examine the associations among sleep duration, sleep architecture or circadian rhythm of the sleep-wake cycle, and glucose metabolism in children, adolescents, and young adults with CRSWD. This cross-sectional observational study of 124 patients with CRSWD took place at Hyogo Children's Sleep and Development Medical Research Center in Hyogo, Japan. The patients underwent a 3-hour oral glucose tolerance test, anthropometric measurements, sleep-log analyses, and polysomnography. Analysis of covariance models were used to assess the association between sleep architecture or circadian rhythm of sleep-wake cycle and glucose/insulin homeostasis, adjusted for confounding variables such as age, gender, standardized body mass index, and sleep apnea index. Impaired glucose tolerance was detected in 25.8% of all patients with CRSWD. After adjustment for confounding variables, we found a negative association between total s...Continue Reading

References

May 26, 1999·Sleep·K McGrawJ H Herman
Oct 30, 1999·Lancet·K SpiegelE Van Cauter
Mar 15, 2002·The New England Journal of Medicine·Ranjana SinhaSonia Caprio
Sep 25, 2003·Sleep Medicine Reviews·Majid MirmiranRonald L Ariagno
Oct 28, 2003·Diabetes Care·Saul GenuthUNKNOWN Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
Jun 4, 2004·The New England Journal of Medicine·Ram WeissSonia Caprio
May 9, 2006·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·G ValerioP Rubba
Mar 27, 2007·Sleep Medicine·Stephanie J CrowleyMary A Carskadon
Nov 29, 2007·Sleep·Timothy I MorgenthalerUNKNOWN Standards of Practice Committee of the American Academy of Sleep Medicine
Jan 4, 2008·Proceedings of the National Academy of Sciences of the United States of America·Esra TasaliEve Van Cauter
Mar 4, 2009·Proceedings of the National Academy of Sciences of the United States of America·Frank A J L ScheerSteven A Shea
Jan 1, 2007·Sleep Medicine Clinics·Mary Ip, Babak Mokhlesi
Sep 1, 2007·Sleep Medicine Clinics·Scott A Rivkees
Feb 18, 2010·Sleep Medicine Clinics·Suzanne E Beck, Carole L Marcus
Mar 9, 2010·PloS One·Marietta KeckeisThomas Pollmächer
Jul 7, 2010·Archives of Pediatrics & Adolescent Medicine·Judith A OwensPatricia Moss
Dec 15, 2010·The Journal of Pediatrics·Sogol JavaheriSusan Redline
Sep 22, 2011·Diabetes Care·Dorit KorenLee J Brooks
Sep 24, 2011·Molecular and Cellular Endocrinology·Christopher J MorrisFrank A J L Scheer
Oct 16, 2012·Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine·Richard B BerryUNKNOWN American Academy of Sleep Medicine
Oct 27, 2012·Neurologic Clinics·Lirong Zhu, Phyllis C Zee
Jan 23, 2013·Sleep Medicine·Roseanne ArmitageRobert Hoffmann
Apr 4, 2013·JAMA : the Journal of the American Medical Association·Ciaran J McMullanJohn P Forman
Jul 3, 2013·Sleep·Lars KlingenbergAnders Sjödin
Mar 19, 2014·Annals of the New York Academy of Sciences·Sirimon Reutrakul, Eve Van Cauter
Mar 25, 2014·Journal of Pineal Research·J Cipolla-NetoR J Reiter
May 24, 2014·Diabetes·Christopher S Colwell, Aleksey V Matveyenko
Nov 16, 2014·Current Diabetes Reports·Dorit KorenBabak Mokhlesi
Apr 4, 2015·Diabetology & Metabolic Syndrome·Anne Briançon-MarjolletJan Polak
Oct 16, 2015·Sleep Medicine·Karen A Matthews, Elizabeth J M Pantesco
Apr 16, 2016·Trends in Endocrinology and Metabolism : TEM·Jingyi Qian, Frank A J L Scheer
May 10, 2017·Nutrition & Diabetes·C Dutil, J-P Chaput
Dec 3, 2017·Metabolism: Clinical and Experimental·Eleonora PoggiogalleCourtney M Peterson
Dec 12, 2018·Nature Reviews. Endocrinology·Dirk Jan StenversAndries Kalsbeek
Aug 30, 2019·Journal of Family Medicine and Primary Care·Anita RawatPrithvi Kumar Singh

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Apr 26, 2021·Chest·Jessica BergerSapna R Kudchadkar

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