Inappropriate prescription of intravenous antibiotics at a tertiary children's hospital in China.

Minerva Pediatrics
Yan WangZhiping Li

Abstract

Antibiotics are one of the most frequently prescribed medication classes worldwide. Inappropriate prescription of antibiotics has increased the risk of drug-resistant infections and associated mortality. The aim of this study was to examine the patterns of intravenous antibiotics prescribing in emergency and outpatient departments of a tertiary children's hospital in China. Data on intravenous prescriptions dispensed by the emergency and outpatient department from January 1, 2015 to May 31, 2016 were extracted from the information system of the Children's Hospital of Fudan University. Prevalence of intravenous antibiotics use and the suitability of intravenous antibiotic prescription were evaluated on the basis of a completed microbiological examination, antibiotics susceptibility testing, and dose prescribed for patients diagnosed with pneumonia, acute bronchitis, fever, and acute upper respiratory infection (AURI) patients. The prescription rate was expressed as the number of intravenous antibiotic prescriptions per total number of prescriptions. Overall, 94.2% of pediatric patients and 78.5 % of issued intravenous prescriptions were for antibiotics. beta-lactam antibacterial (90.5 %) and macrolides (18.5 %) were the most com...Continue Reading

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