PMID: 9531227Apr 8, 1998Paper

Incidence and consequences of pregnancy in women with known duration of HIV infection. Italian Seroconversion Study Group

Archives of Internal Medicine
M B AlliegroG Rezza

Abstract

The increasing incidence of human immunodeficiency virus (HIV) infection in women of childbearing age led us to evaluate whether pregnancy affects the natural history of this disease. To conduct a prospective study of women with known dates of HIV seroconversion to describe the incidence and outcome of pregnancy and to assess differences according to age and exposure group. To compare the rate of disease progression between pregnant and nonpregnant women. All participants, recruited from 14 clinical centers in Italy, had documented HIV-seronegative test results followed by confirmed positive test results within 2 years. A total of 331 women, who had seroconversion between 1981 and 1994, were followed up for a median of 5.5 years from seroconversion; 94 developed HIV-related diseases, 47 developed acquired immunodeficiency syndrome, and 53 had at least 1 CD4 cell count lower than 0.10 x 10(9)/L (< 100 cells/mm3). Thirty-eight women (11.5%) were pregnant at the time of HIV seroconversion and 31 (9.4%) became pregnant after HIV seroconversion (cumulative incidence of pregnancy within 8 years of seroconversion, 28.9%; 95% confidence interval, 21.6%-36.2%). Forty-five (65.2%) of the 69 pregnancies were carried to term. There were no...Continue Reading

Citations

Jul 16, 2003·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Jacob GiladFrancisc Schlaeffer
Oct 13, 2006·Current Opinion in Infectious Diseases·G Tudor-Williams, E G Lyall
Mar 29, 2002·AIDS·Birgit H B van BenthemUNKNOWN European Study on the Natural History of HIV Infection in Women and the Swiss HIV Cohort Study
May 10, 2001·Clinical Obstetrics and Gynecology·L Ahdieh
May 20, 1999·Sexually Transmitted Diseases·R G GriffinG L Hoff
Apr 26, 2007·AIDS·Charles S MorrisonBarbra A Richardson
Jan 2, 2007·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Marisa TungsiripatJudith A Aberg
Oct 2, 2007·Journal of Women's Health·Susan AllenAndre Declercq
Feb 7, 2003·Journal of Obstetric, Gynecologic, and Neonatal Nursing : JOGNN·Anne Katz
Oct 16, 2007·Lancet·Kirrin GillAnju Malhotra
May 16, 2007·Infectious Disease Clinics of North America·Erna Milunka Kojic, Susan Cu-Uvin
Aug 19, 2007·Tropical Medicine & International Health : TM & IH·Van der Paal LieveHeiner Grosskurth
Oct 3, 2006·Lancet·Carine RonsmansUNKNOWN Lancet Maternal Survival Series steering group
Oct 2, 2003·American Journal of Obstetrics and Gynecology·Howard MinkoffBruce Thompson

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