Incidence and duration of incident oropharyngeal gonorrhoea and chlamydia infections among men who have sex with men: prospective cohort study.

Sexually Transmitted Infections
Eric P F ChowChristopher K Fairley

Abstract

This prospective cohort study aimed to determine the natural history and incidence of oropharyngeal gonorrhoea and chlamydia among a cohort of men who have sex with men (MSM) over a 12-week period, and to examine risk factors associated with incident oropharyngeal infections. MSM either aged ≥18 years and had a diagnosis of oropharyngeal gonorrhoea by nucleic acid amplification test (NAAT) in the past 3 months or aged 18-35 years who were HIV-negative taking pre-exposure prophylaxis (PrEP) were eligible for this study. Enrolled men were followed up for 12 weeks. Oropharyngeal swabs were collected at week 0 (baseline) and week 12 (end of study). Between these time points, weekly saliva specimens and the number of tongue kissing, penile-oral and insertive rimming partners were collected by post. Oropharyngeal swabs and saliva specimens were tested by NAAT for Neisseria gonorrhoeae and Chlamydia trachomatis. Poisson regression was performed to examine the risk factors (weekly number of partners) associated with incident oropharyngeal gonorrhoea. A total of 100 MSM were recruited. The incidence of oropharyngeal gonorrhoea and chlamydia was 62 (95% CI 37 to 105) and 9 (95% CI 2 to 35)/100 person-years, respectively. The median durat...Continue Reading

References

Jul 15, 2016·Journal of Clinical Microbiology·Eric P F ChowChristopher K Fairley
Dec 17, 2016·Emerging Infectious Diseases·Christopher K FairleyEric P F Chow
Apr 10, 2019·JAMA : the Journal of the American Medical Association·Michael W TraegerUNKNOWN PrEPX Study Team
Jul 22, 2019·The Lancet Infectious Diseases·Christopher K FairleyEric P F Chow

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Citations

Apr 13, 2021·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Connor AllenEric P F Chow
May 30, 2021·The Lancet Infectious Diseases·Eric P F Chow, Christopher K Fairley

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