Incidence and evolution of sepsis-induced cardiomyopathy in a cohort of patients with sepsis and septic shock.

Medicina intensiva
I NarváezM Magro

Abstract

The aim of this study was to establish the incidence of septic cardiomyopathy (SM) in patients with sepsis and septic shock, to describe its characteristics and testing its evolution. Prospective cohort study. We included 57 consecutive patients admitted to Intensive Care Unit, who met criteria of sepsis and septic shock. Clinical and biochemical variables were analyzed. An echocardiogram was performed in the first 24hours of admission, determining myocardial function parameters, and if the patients had left ventricular ejection fraction (LVEF)<50%) a second echocardiogram was performed. Intensive medical and surgical Care Service for Adults in University Hospital. The mean age of the patients was 62,1±16,3 years. 58% were males. 22.8% had left ventricular dysfunction. The mean LVEF in patients with MS was lower than those without SM (34.1±10.6 vs 60.7±6.94%, P<.001), with complete recovery, in survivors, after the acute event (LVEF at discharge 56.1±6.3%, P=.04). Patients with SM had higher levels of procalcitonin (47.1±35.4 vs 18.9±24.5; P=.02) and higher score on the Sequential Organ Failure Assessment (SOFA score) (9.91±3.82 vs 7.47±3.41; P=.037). Mortality was not significantly different between both groups [4 (30.8%) vs 4...Continue Reading

Citations

Feb 9, 2021·Seminars in Cardiothoracic and Vascular Anesthesia·Nirvik PalMiklos D Kertai

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