Incidence and Immunologic Analysis of Coronavirus Disease (COVID-19) in Hemodialysis Patients:A Single-Center Experience

Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation
Hande ArslanMehmet Haberal

Abstract

COVID-19 is a great threat to the modern world and significant threat to immunocompromised patients, including patients with chronic renal failure. We evaluated COVID-19 incidence among our hemodialysis patients and investigated the most probable immune mechanisms against COVID-19. Başkent University has 21 dialysis centers across Turkey, with 2420 patients on hemodialysis and 30 on peritoneal dialysis. Among these, we retrospectively evaluated 602 patients (257 female/345 male) with chronic renal failure receiving hemodialysis as renal replacement therapy; 7 patients (1.1%) were infected with SARS-CoV-2. We retrospectively collected patient demographic characteristics, clinical data, and immunological factors affecting the clinical course of the disease. We divided patients into groups and included 2 control groups (individuals with normal renal functions): group I included COVID-19-positive patients with normal renal function, group II included COVID-19-positive hemodialysis patients, group III included COVID-19-negative hemodialysis patients, and group IV included COVID-19-negative patients with normal renal function. Lymphocyte subsets in peripheral blood and typing of human leukocyte antigens were analyzed in all groups, w...Continue Reading

References

Sep 13, 2003·BMC Medical Genetics·Marie LinChun-Hsiung Huang
Sep 3, 2004·Current Opinion in Immunology·Lorenzo Moretta, Alessandro Moretta
Apr 6, 2005·The Journal of Experimental Medicine·Sumati Rajagopalan, Eric O Long
Nov 22, 2007·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Henri Vacher-CoponatPascale Paul
Jan 10, 2013·Annual Review of Immunology·Stephanie Jost, Marcus Altfeld
Apr 12, 2019·Frontiers in Immunology·Jan-Eric TurnerAndrew J Kassianos
Apr 14, 2020·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Mehmet Haberal
Apr 14, 2020·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Faik SarialiogluMehmet Haberal
May 5, 2020·Hemodialysis International·Pasquale EspositoFrancesca Viazzi

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Citations

Sep 25, 2020·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Dimitrios GiannisDimitrios Moris
Nov 5, 2020·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Aydincan AkdurMehmet Haberal
Dec 5, 2020·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Dimitrios Giannis, Dimitrios Moris
Dec 5, 2020·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Ahmad MahamidSander Florman
Feb 19, 2021·Journal of Gastrointestinal Cancer·Adem TuncerSezai Yilmaz
Oct 13, 2020·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Chih-Cheng LaiPo-Ren Hsueh
Jul 31, 2021·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Vivek B KuteVijay V Navadiya
Sep 22, 2021·Experimental and Clinical Transplantation : Official Journal of the Middle East Society for Organ Transplantation·Vivek B KuteVineet V Mishra

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