Incidence, Characteristics, and Clinical Course of Device-Related Thrombus After Watchman Left Atrial Appendage Occlusion Device Implantation in Atrial Fibrillation Patients

JACC. Clinical Electrophysiology
Shunsuke KuboSaibal Kar

Abstract

This study investigated characteristics and clinical impact of device-related thrombus formation after Watchman device implantation in atrial fibrillation (AF) patients. Left atrial appendage occlusion using the Watchman device is an effective alternative to anticoagulation for stroke prevention in AF patients. However, device-related thrombus formation remains an important concern after Watchman implantation. From 2006 to 2014, 119 consecutive AF patients underwent Watchman implantation. Transesophageal echocardiographic (TEE) follow-up was scheduled at 45 days, at 6 months, and at 12 months after the procedure. The incidence, characteristics, and clinical course of device-related thrombus formation detected by TEE were assessed. Follow-up TEE identified thrombus formation on the Watchman device in 4 patients (3.4%). The prevalence of chronic AF was 100% in patients with thrombus, which was higher than that for patients without thrombus (40.0%). Deployed device size was numerically larger in patients with thrombus (29.3 ± 3.8 mm vs. 25.7 ± 3.2 mm, respectively). All patients with thrombus discontinued any of the anticoagulant/antiplatelet therapy which was required under the study protocol. After restarting or continuing warfa...Continue Reading

References

Feb 1, 1996·The Annals of Thoracic Surgery·J L Blackshear, J A Odell
Jul 2, 2003·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·William A ZoghbiUNKNOWN American Society of Echocardiography
Mar 29, 2011·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·Srilatha AyiralaDavid I Silverman
Feb 16, 2012·European Heart Journal·Maurizio GaspariniRenato Bragato
Jun 22, 2013·JACC. Cardiovascular Interventions·Bjoern PlichtRaimund Erbel
Feb 14, 2014·Circulation. Cardiovascular Imaging·Masayoshi YamamotoKazutaka Aonuma
Feb 20, 2014·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Simon Cheung Chi LamHorst Sievert
Nov 17, 2014·JAMA : the Journal of the American Medical Association·Vivek Y ReddyUNKNOWN PROTECT AF Steering Committee and Investigators

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Citations

Jul 2, 2019·Journal of Cardiovascular Electrophysiology·Bhradeev SivasambuRonald D Berger
Sep 15, 2019·Current Treatment Options in Cardiovascular Medicine·Dennis Toy, David M Naeger
Oct 2, 2020·Curēus·Kyaw M HlaingKamran Riaz
May 13, 2018·Circulation·Srinivas R DukkipatiVivek Y Reddy
Mar 31, 2021·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Yasir Abdul GhaffarRamesh Daggubati
Aug 3, 2021·Annals of Thoracic and Cardiovascular Surgery : Official Journal of the Association of Thoracic and Cardiovascular Surgeons of Asia·Taira YamamotoAtsushi Amano
Oct 29, 2021·Circulation. Cardiovascular Interventions·David H YooMatthew J Price
Aug 19, 2020·Cardiology·Demilade AdedinsewoPragnesh Parikh

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