Incidence, demographics, types and risk factors of dry eye disease in India: Electronic medical records driven big data analytics report I

The Ocular Surface
Pragnya Rao DonthineniSayan Basu

Abstract

To describe the incidence, demographics, types and risk-factors of dry eye disease (DED) in patients presenting to a multi-tier ophthalmology hospital network in India. This was an observational hospital-based study of 1,458,830 new patients presenting between 2010 and 2018. Patients with recent onset of both symptoms and signs, as defined by the tear film and ocular surface society dry eye work shop (TFOS DEWS) II guidelines, were considered as DED subjects. The data was prospectively collected using an electronic medical record system. Multiple logistic regression with odds ratio (OR) estimation was performed to identify the high risk-factors of DED. Overall, 21,290 (1.46%) patients were diagnosed with recent-onset DED. The incidence of DED was 2688 and 16,482 per million population in children and adults, respectively (p < 0.0001). While incidence was significantly greater in males in 3rd, 4th, 9th and 10th decade (p < 0.03), it was greater in females in 5th and 6th decade (p < 0.0001) of life. Classified etiologically 35.5%, 20.6% and 39.9% of patients had evaporative, aqueous deficient and mixed type of DED, respectively. Age (OR 3.7-13.5), urban residence (OR 1.6), professional work (OR 1.5); homemaking (OR 1.42), retirem...Continue Reading

Citations

Feb 15, 2020·Indian Journal of Ophthalmology·Atul KumarDivya Agarwal
Oct 21, 2019·The British Journal of Ophthalmology·Swapna S ShanbhagSayan Basu
Jun 27, 2020·Indian Journal of Ophthalmology·Samrat ChatterjeeArpit Sharma
Sep 14, 2020·The British Journal of Ophthalmology·Swati SinghSayan Basu
Nov 25, 2020·The British Journal of Ophthalmology·Anthony Vipin Das, Sayan Basu
Oct 30, 2020·Frontiers in Medicine·Pragnya R DonthineniSayan Basu
Feb 19, 2021·The British Journal of Ophthalmology·Swati SinghSayan Basu
Apr 17, 2021·The Ocular Surface·Archana Padmanabhan NairSwaminathan Sethu
Apr 24, 2021·PloS One·Michael MooreDaniel I Flitcroft
Apr 30, 2021·Indian Journal of Ophthalmology·Samrat ChatterjeeRushi Kandoi
Oct 29, 2021·Indian Journal of Ophthalmology·Anthony Vipin Das
Nov 28, 2021·Indian Journal of Ophthalmology·Samrat Chatterjee, Deepshikha Agrawal

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cell Migration

Cell migration is involved in a variety of physiological and pathological processes such as embryonic development, cancer metastasis, blood vessel formation and remoulding, tissue regeneration, immune surveillance and inflammation. Here is the latest research.