Abstract
Ovarian metastasis are frequently encountered during the course of breast cancer, concerning one woman in five among those suffering from the disease. These secondary ovarian lesions are usually small and bilateral with a non-cystic pattern and are more likely to be from primary infiltrating lobular carcinoma of the breast. Distinction between ovarian metastasis and primary ovarian cancer may sometimes be difficult and require immunohistochemical stains with various monoclonal antibodies. Primary ovarian cancer remains preponderant however, even in a woman with breast cancer. From a clinical point of view, ovarian metastasis are frequently unknown except in case of peritoneal dissemination. Trans-vaginal ultrasonography scan is the best examination when clinical signs give cause to suspect ovarian tumour. Although, systematic ultrasonography screening, as well as blood screening program using CA 125 and CA 15-3, should not be recommended because they lack sensibility and are too expensive. The development of ovarian metastasis during the course of a breast primary carcinoma is a negative prognostic factor with regards to the presence or absence of peritoneal dissemination.
Citations
Dec 19, 2018·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·W TianY Deng
Dec 31, 2009·Cancer·Veronique BigorieEmmanuel Barranger
Dec 25, 2012·Journal of Assisted Reproduction and Genetics·Mikkel RosendahlClaus Yding Andersen
Apr 28, 2019·Medicine·Jiang WangYongchuan Deng
Oct 30, 2013·Nature Reviews. Endocrinology·Jacques Donnez, Marie-Madeleine Dolmans
Aug 31, 2013·Journal of Assisted Reproduction and Genetics·V LuyckxM M Dolmans
Mar 8, 2016·Archives of Gynecology and Obstetrics·Inge T A PetersPeter J K Kuppen
Jan 27, 2017·PloS One·Inge T A PetersJ Baptist Trimbos
May 25, 2006·The Oncologist·Murat Sonmezer, Kutluk Oktay
Nov 1, 2012·Annals of Oncology : Official Journal of the European Society for Medical Oncology·E MunzoneF Nolé
Mar 6, 2017·Gynécologie, Obstétrique, Fertilité & Sénologie·M-L BergaminiC Mathelin
Jan 29, 2011·Fertility and Sterility·S Samuel KimCarol Fabian